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technical support for your product directly (links go to external sites):Thank you for your interest in spreading the word about The BMJ.NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. Although elevations in prolactin associated with clozapine are minimal relative to many other antipsychotics, interference with proper lactation is … Interferes with binding of dopamine to DUtilized for treatment of schizophrenia uncontrolled by other agents.Indicated only in the management of severely ill schizophrenic patients who have failed to respond to other neuroleptic agents.Schizo-affective disorder, severe obsessive-compulsive disorder, bipolar disorder, dementia-related behavioral disorders.Severe CNS depression, blood dyscrasia, history of bone marrow depression; patients with myeloproliferative disorders, uncontrolled An antipsychotic agent other than clozapine would be preferred due to the possibility of clozapine-induced agranulocytosis or other adverse events in the nursing infant; guidelines support that lactating women taking clozapine should not breastfeed. Clozapine is used to treat schizophrenia after other treatments have failed. - Psychosis in Parkinson’s.

Cetirizine HCl (Zyrtec) is an antihistamine used in the management of seasonal allergic rhinitis. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug … 0000018442 00000 n clozapine.) 0000008407 00000 n Nursing staff who administer clozapine must know the indications, safe use and screening processes for clozapine and data entry requirements. Clozapine is an antipsychotic medicine.

neurological disease, tardive dyskinesia, previous history of agranulocytosis; surgery, glaucoma, infection, pregnancy (category View a sample pharm lesson now! Condition or … 0000019991 00000 n NICE (2015) guidance advises that Clozapine is a specialist medication, indicated to treat schizophrenia in patients unresponsive to, or intolerant of, conventional antipsychotic drugs. 7 0 obj <> endobj xref 7 27 0000000016 00000 n

Arrhythmias, GI disorders, narrow-angle glaucoma, hepatic and renal impairment, prostatic hypertrophy, history of seizures; - Intolerance/unresponsiveness to conventional antipsychotics.- Neutropenia and potentially fatal agranulocytosis.- Leucopenia, leucocytosis, agranulocytosis, eosinophilia.- Circulatory collapse, arrhythmias, myocarditis, pericarditis.- Differential blood counts must be normal on commencement and monitored regularly.- Due to potential for myocarditis and cardiomyopathy, patients should have:- Specialist examination if there are any cardiac problems; - Investigations for myocarditis or cardiomyopathy in the presence of tachycardia.- Stop taking if cardiomyopathy or myocarditis is suspected.- Use with caution in conjunction with drugs causing constipation.- Withdraw drug over 14 days to prevent rebound psychosis.- Patients must immediately report symptoms of infection, especially flu-like symptoms.- Avoid hot baths or showers as hypotension can occur.- Oral hygiene is important to avoid oral candidiasis.- Avoid overexposure to the sun as heatstroke can occur.Nurses should refer to manufacturer’s summary of product characteristics and to appropriate local guidelines  Wandai Maposa, haemophilia lead clinical nurse specialist at St George’s Hospital… In … What happens if I overdose with Clozapine? - Schizophrenia. If using orally disintegrating tablets, begin with 1/2 (12.5 mg) of a 25-mg … It is intended as a third line treatment for chronic

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