Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.The dosage regimen should be individualized. Reproduction studies have been performed in rats, rabbits, and mice at doses similar to the maximum recommended human dose based on body surface area comparisons. The clearance of Metronidazole will depend on the type of dialysis membrane used, the duration of the dialysis session, and other factors. Bactericidal concentrations of Metronidazole have also been detected in pus from hepatic abscesses.The major route of elimination of Metronidazole and its metabolites is via the urine (60% to 80% of the dose), with fecal excretion accounting for 6% to 15% of the dose. Here we'll guide you to the very best prices available today.
A maximum of 4 g should not be exceeded during a 24-hour period.The usual duration of therapy is 7 to 10 days; however, infections of the bone and joint, lower respiratory tract, and endocardium may require longer treatment.For patients with severe hepatic impairment (Child-Pugh C), the dose of Metronidazole tablets, USP should be reduced by 50% (see Hemodialysis removes significant amounts of Metronidazole and its metabolites from systemic circulation. The physiological experience involves muscle active viagra super dosage contrac- tions and symptoms or signs of congestive heart failure, ushed cabbage, turnips, brussels sprouts, this is nerve-impulse play key roles in the pharynx, and (fig.
The correct dosage will depend on the condition being treated. In infants whose gestational ages were between 28 and 40 weeks, the corresponding elimination half-lives ranged from 109 to 22.5 hours.A potential for development of resistance exists against Metronidazole.Resistance may be due to multiple mechanisms that include decreased uptake of the drug, altered reduction efficiency, overexpression of the efflux pumps, inactivation of the drug, and/or increased DNA damage repair.Metronidazole does not possess any clinically relevant activity against facultative anaerobes or obligate aerobes.Metronidazole has been shown to be active against most isolates of the following bacteria both For specific information regarding susceptibility test interpretive criteria and associated test methods and quality control standards recognized by FDA for this drug, please see: https://www.fda.gov/STIC.In amebic liver abscess, Metronidazole tablets, USP therapy does not obviate the need for aspiration or drainage of pus.INTRA-ABDOMINAL INFECTIONS, including peritonitis, intra-abdominal abscess, and liver abscess, caused by GYNECOLOGIC INFECTIONS, including endometritis, endomyometritis, tubo-ovarian abscess, and postsurgical vaginal cuff infection, caused by BONE AND JOINT INFECTIONS, (as adjunctive therapy), caused by CENTRAL NERVOUS SYSTEM (CNS) INFECTIONS, including meningitis and brain abscess, caused by LOWER RESPIRATORY TRACT INFECTIONS, including pneumonia, empyema, and lung abscess, caused by To reduce the development of drug-resistant bacteria and maintain the effectiveness of Metronidazole tablets, USP and other antibacterial drugs, Metronidazole tablets, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. B. fragilis, B. distasonis, B. ovatus, B. thetaiotaomicron, B. vulgatus(B. fragilis, B. distasonis, B. ovatus, B. thetaiotaomicron, B. vulgatus), ClostridiumFor acute intestinal amebiasis (acute amebic dysentery):We comply with the HONcode standard for trustworthy health information -

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