Theophylline is usually taken twice a day, although some doctors may prescribe just one dose a day. Passive smoke exposure has also been shown to increase theophylline clearance by up to 50%. In general, patients who experience an acute overdose are less likely to experience seizures than patients who have experienced a chronic overdosage, unless the peak serum theophylline concentration is >100 mcg/mL. Do not double the dose to catch up.Store at room temperature away from light and moisture.
Corticosteroids act, at least in part, by recruitment of histone deacetylases (HDACs) to the site of active inflammatory gene transcription.
Careful attention to dose reduction and frequent monitoring of serum theophylline concentrations are required in elderly patients (see The clearance of theophylline is very low in neonates (see Gender differences in theophylline clearance are relatively small and unlikely to be of clinical significance. Some of the adverse effects associated with theophylline appear to be mediated by inhibition of PDE III (e.g., hypotension, tachycardia, headache, and emesis) and adenosine receptor antagonism (e.g., alterations in cerebral blood flow).Theophylline increases the force of contraction of diaphragmatic muscles. Additionally, there are no teratogenicity studies in non-rodents (e.g., rabbits). New interactions are continuously being reported for theophylline, especially with new chemical entities.
Theophylline relaxes smooth muscle in the respiratory tract and suppresses airway stimuli. Theophylline, also known as 1,3-dimethylxanthine, is a phosphodiesterase inhibiting drug used in therapy for respiratory diseases such as chronic obstructive pulmonary disease and asthma under a variety of brand names. Do not increase your dose, take this drug more often, or stop taking it without first consulting your doctor.Tell your doctor right away if you have any serious side effects, including: nausea/vomiting that doesn't stop, fast/slow/irregular heartbeat, Get medical help right away if you have any very serious side effects, including: This is not a complete list of possible side effects.
Consult your Are you considering switching to Theophylline ANHYDROUS?Are you planning to see a doctor about switching your medication?How long have you been taking Theophylline ANHYDROUS?Are you planning to see a doctor about switching your medication?Selected from data included with permission and copyrighted by First Databank, Inc. Because of marked individual differences in the rate of theophylline clearance, the dose required to achieve a peak serum theophylline concentration in the 10-20 mcg/mL range varies fourfold among otherwise similar patients in the absence of factors known to alter theophylline clearance (e.g., 400-1600 mg/day in adults <60 years old and 10-36 mg/kg/day in children 1-9 years old). Theophylline clearance has been shown to increase by approximately 50% in young adult tobacco smokers and by approximately 80% in elderly tobacco smokers compared to non-smoking subjects. Respbid, T-Phyl, Aerolate III, Slo-Bid Gyrocaps, Slo-Phyllin, Theobid, Theo-Dur, Theolair, Theovent, Bronkodyl, Theo-X, Theo-Time, Theochron, Slo-Phyllin 125, Theoclear L.A.-130, Aerolate JR, Theolair-SR, Theoclear L.A.-260, Quibron-T, Quibron-T/SR, Uniphyl, Uni-Dur, Aerolate SR, Slo-Phyllin 80, Theoclear-80, Theo-Dur Sprinkles, Theosol-80, Asmalix, Aquaphyllin, Truxophyllin, Slo-Phyllin 250, TheoCapWe comply with the HONcode standard for trustworthy health information -
Overdose can also occur slowly over time if your daily doses are too high. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Call your doctor for medical advice about side effects. Theophylline is used to treat lung diseases such as asthma and COPD (bronchitis, emphysema).It must be used regularly to prevent wheezing and shortness of breath. This medication …
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