Bioidentical progesterone is not known to cause addiction nor decrease restorative sleep. [Not just that, it is critical to the understanding of any drug, dietary supplement, homeopathic remedy, or TCM herb.
Indeed, FDA has received adverse event reports that reveal harmful variations in compounding.In addition to problems associated with compounding itself, the report finds the evidence does not support the cBHT marketing hype. For starters:Many patients believe that bioidentical means that plants are the source of the hormones, however, it is the chemical structure and not the source that determines whether a hormone is bioidentical. For the purpose of this review, bioidentical hormones are defined as hormones identical in structure to human hormones. It is important to realize that these symptoms will disappear in two weeks to three cycleDosage Instructions for Bioidentical USP Progesterone Creams like PhytoGestDosage for Women who are Perimenopausal (still menstruating with menopausal and Estrogen Dominance Symptoms and/or PMS but not ovulating)Do I need a break from using the cream each month? Also, because it is common for bioidentical progesterone to cause feelings of sleepiness, women should take the dosage right before going to sleep. Unfortunately, the recommendation is addressed to providers, not regulators, and will likely be ignored by physicians, naturopaths, and other healthcare providers who prescribe cBHT, except for perhaps the few who were genuinely unaware of the lack of evidence and care about such things. determining definitive bioavailability of those preparations [is] difficult. Their report, some 350 pages long, details the committee’s findings and makes recommendations, including restricting the use of cBHT preparations.hormones that are chemically and structurally identical to those produced by the human body, with the The vast majority of FDA-approved BHT products are indicated for treating symptoms of menopause and male hypogonadism, and the report focuses on cBHT use for these indications as well.
* “Clinical utility” is defined as “A multidimensional construct that reflects evidence about safety, effectiveness, and therapeutic need. Exploring issues and controversies in the relationship between science and medicineA National Academies report finds widely-marketed compounded hormone replacement therapies lack evidence of safety and effectiveness, and recommends restriction of their use.While the FDA has approved dozens of hormone therapy products for men and women, such as estrogen, progesterone, and testosterone, many health care providers and patients have turned to compounded hormone preparations as an alternative. This can temporarily cause buildup of the endmetrium of the uterus, causing spotting and irregular bleeding. Proper dosage and compliance are essential to correct your low progesterone level and achieve best results.
These statements have not been evaluated by the Food and Drug Administration.These products are not intended to diagnose, treat, cure, or prevent any disease. If the progesterone cream is used out of sequence, it will interfere with the menstrual cycle.For non-menstruating women, it is recommended by Dr. Lee that the cream be used for three weeks and a break of one week.In premenopausal women, progesterone deficiency causes a “tuning down” of estrogen receptors, and progesterone cream reactivates these receptor sites. ]The committee also accepted public testimony and written comments. However, as the committee notes, marketed claims for cBHT also include the treatment of conditions related to “antiaging” (longer, fuller hair; smoother skin), sexual health, joint pain, general chronic pain, insomnia, cardiovascular disease, and mental health disorders.As the report points out, current evidence-based clinical practice guidelines recommend the use of FDA-approved products for treatment of menopausal symptoms and male hypogonadism.
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