0000030204 00000 n Convulsions should be treated with diazepam or other suitable anticonvulsant.Pharmacotherapeutic group: Antihistamines for systemic use; Phenothiazine derivatives, ATC code: R06AD02Potent, long acting, antihistamine with additional anti-emetic central sedative and anti-cholinergic properties.Promethazine is distributed widely in the body. 0000024987 00000 n The following CIOMS frequency rating is used: Very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1000 to <1/100); rare (≥1/10 00 to <1/1000); very rare (<1/10 000), not known (cannot be estimated from the available data).Side effects may be seen in a few patients: drowsiness, dizziness, restlessness, headaches, nightmares, tiredness, and disorientation. startxref When suggestions are available use up and down arrows to review and ENTER to select. Treatment is otherwise supportive with attention to maintenance of adequate respiratory and circulatory status. Children over 10 years and adults (including elderly) 25 mg to be taken the night before the journey.

• An IV push of Phenergan 25mg is given @ 0830. Phenergan may thicken or dry lung secretions and impair expectoration. This information is intended for use by health professionalsEach tablet contains 25mg of the active substance Promethazine hydrochloride. 0000008421 00000 n 0000019842 00000 n 0000025065 00000 n Use with care in patients with severe coronary artery disease, narrow angle glaucoma, epilepsy or hepatic and renal insufficiency. %%EOF 0000029248 00000 n • Infliximab (Remicaid®) is then infused 0900 ‐ 1200. Promethazine is contraindicated for use in children less than two years of age because of the potential for fatal respiratory depression.. Phenergan should be avoided in patients taking monoamine oxidase inhibitors up to 14 days previously. Strong sunlight should be avoided during treatment. 0000029978 00000 n

0000001883 00000 n The elderly are particularly susceptible to the anticholinergic effects and confusion due to promethazine.


Convulsions may occur in both adults and children: coma or excitement may precede their occurrence. 0000002293 00000 n trailer They are characterised in children by various combinations of excitation, ataxia, incoordination, athetosis and hallucinations, while adults may become drowsy and lapse into coma. 0000010832 00000 n 0000003340 00000 n Date of first authorisation/renewal of the authorisationStart typing to retrieve search suggestions. 4.5 Interaction with other medicinal products and other forms of interaction6.6 Special precautions for disposal and other handling9.

It enters the brain and crosses the placenta.

Phenergan may interfere with immunological urine pregnancy tests to produce false-positive or false-negative results. 0000000016 00000 n However, there are risks of neonatal irritability and excitement.Because the duration of action may be up to 12 hours, patients should be advised that if they feel drowsy they should not drive or operate heavy machinery. IV Drug Compatibility Chart A Alteplase (Activase, rTPA) Amiodarone (Cordarone) Argatroban Atropine Calcium chloride Diltiazem (Cardizem) Dobutamine (Dobutrex) Dopamine Epinephrine (Adrenalin) Esmolol (Brevibloc) Furosemide (Lasix) Heparin Insulin (regular) Lidocaine (Xylocaine) Lorazepam (Ativan) Magnesium Sulfate Phenergan should be discontinued at least 72 hours before the start of skin tests as it may inhibit the cutaneous histamine response thus producing false-negative results.Phenergan should not be used in pregnancy unless the physician considers it essential. h�bbbd`b``Ń3� ������ � 0000015118 00000 n

Pale blue film coated tablets marked PN 25 on one side.As symptomatic treatment for allergic conditions of the upper respiratory tract and skin including allergic rhinitis, urticaria and anaphylactic reactions to drugs and foreign proteins. Alcohol should be avoided during treatment. Phenergan should not be given to patients with a known hypersensitivity to promethazine or to any of the excipients.

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