If you have blurred vision, it may return to normal after you stop taking this medication. Drugs like beta-blockers and diuretics like hydrochlorothiazide can sometimes cause erectile dysfunction. Minoxidil also must be used in conjunction with a thiazide (e.g., hydrochlorothiazide 50 mg twice daily, chlorthalidone 50-100 mg once daily) or loop diuretic (e.g., furosemide 40 mg twice daily) when initiating minoxidil therapy in patients dependent on renal function for maintenance of sodium and water balance. Winter Flu Jab Service. Diuretics have been used at the following dosages when starting therapy with Minoxidil: hydrochlorothiazide (50 mg, b.i.d.) No symptoms, evidence of myocardial damage, or deterioration of cardiac function have been associated with minoxidil-induced ECG changes.Within 3-6 weeks after initiating minoxidil therapy, hypertrichosis (elongation, thickening, and increased pigmentation of fine body hair) commonly occurs but is not associated with an endocrine abnormality. Minoxidil was FDA approved in 1979 as an oral medication to treat blood pressure problems. Although rapid reduction in blood pressure may precipitate cerebrovascular accidents and myocardial infarction in patients with very severe hypertension, these adverse effects have not been unequivocally associated with minoxidil therapy.Pericardial effusion, sometimes with tamponade, has been observed in about 3% of patients receiving minoxidil who were not on dialysis, especially in those with inadequate or compromised renal function.
Because the safety and efficacy of extemporaneously prepared formulations of topical minoxidil in promoting hair growth have not been fully evaluated and because such preparations may vary in strength and efficacy, the FDA requests that physicians and pharmacists refrain from preparing extemporaneous topical formulations using the commercially available tablets. This drug can cause a fluid or electrolyte imbalance. Livi. By using the FSA debit card, your expenses are auto-adjudicated (electronically approved or disapproved) from the card and you may not need to submit additional receipts to your FSA Administrator. However, if left untreated, certain vision problems can lead to permanent vision loss.If you’re allergic to medications that contain sulfonamide, you shouldn’t take this drug.Hydrochlorothiazide can cause a severe allergic reaction. You may have symptoms such as feeling dizzy when you stand up after sitting or lying down.Talk to your doctor if you’re pregnant or planning to become pregnant. The effect is usually used to therapeutic advantage, but careful adjustment of dosage is necessary when these drugs are used concomitantly. If necessary, dosage is gradually increased at intervals of at least 3 days in increments of 50-100% until optimal blood pressure response is attained. An in vitro cytogenetic assay using Chinese hamster cells at long exposure times yielded equivocal results, but results of a similar assay in human lymphocytes were negative.Oral administration of minoxidil for up to 2 years in mice was associated with an increased incidence of malignant lymphoma in females receiving minoxidil dosages of 10, 25, or 63 mg/kg daily and an increased incidence of hepatic nodules in males receiving minoxidil dosages of 63 mg/kg daily. It is used to help reduce the amount of water in the body by increasing the flow of urine. Angina pectoris may worsen or occur in patients without previous angina, probably due to increased oxygen demand associated with increased heart rate and cardiac output and can usually be prevented by a β-adrenergic blocker or other sympathetic nervous system suppressant. Therefore, this medication is only used when other treatments have not worked well or cannot be taken. There was no evidence of teratogenic effects in rats receiving subcutaneous minoxidil dosages of 80 mg/kg daily (about 2000 times the maximal systemic human exposure achieved with daily administration of topical minoxidil); however, maternal toxicity was observed with this dosage. Hypertrichosis (which appeared as a general increase in bristly hair that was longest in the sacral area) occurred in another infant born to a woman who had received minoxidil as well as metoprolol and prazosin throughout pregnancy. Your doctor will write the number of refills authorized on your prescription.You may need to check your blood pressure at home.
Diuretic effectiveness may be limited, especially in patients with impaired renal function, and a few patients have required 640 mg to 1.2 g of furosemide daily. In children younger than 12 years of age, the usual initial dosage of minoxidil is 0.2 mg/kg (maximum 5 mg) once daily.
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