Clinical and mycological control tests (KOH wet mount and culture) were performed before treatment, at the end of treatment and 4 wks after stopping treatment. This site needs JavaScript to work properly. In the majority of cases, the infecting agent was identified as Trichophyton rubrum (53/64). Malassezia furfur, the fungus causing pityriasis versicolor, has been reported to be sensitive to terbinafine in vitro but although topical therapy is effective in the treatment of pityriasis versicolor, oral therapy is not. Epub 2015 Oct 4.Clin Cosmet Investig Dermatol. Tinea … Pityriasis versicolor (PV), also known as tinea versicolor, is a chronic and benign superficial fungal skin infection caused by Malassezia yeasts, which are part of the many microscopic organisms that normally live on the skin. S. Karger AG, Basel, Switzerland Name must be less than 100 characters Signs and symptoms of infection responded more quickly to oral terbinafine. Select drug class All drug classes - miscellaneous topical agents (3) - azole antifungals (6) - vaginal anti-infectives (4) - topical antifungals (56) This phenomenon was investigated by determining the susceptibility to terbinafine of different M. furfur subgroups in vivo (during topical or oral application) and in vitro. In a clinical trial for interdigital tinea pedis, patients receiving oral terbinafine administered for 1 week achieved the same cure rates as those who received 4 weeks of topical clotrimazole 1% cream application (71%). Wiley Isolates of subgroup A were also markedly more susceptible to terbinafine in laboratory tests. Side-effects following oral administration of the recommended dose of 125 mg b.i.d. 1999 Jul;58(1):179-202. doi: 10.2165/00003495-199958010-00018.Budimulja U, Bramono K, Urip KS, Basuki S, Widodo G, Rapatz G, Paul C.Elewski BE, Cáceres HW, DeLeon L, El Shimy S, Hunter JA, Korotkiy N, Rachesky IJ, Sanchez-Bal V, Todd G, Wraith L, Cai B, Tavakkol A, Bakshi R, Nyirady J, Friedlander SF.J Am Acad Dermatol. 2000 Aug;44(8):2185-6. doi: 10.1128/aac.44.8.2185-2186.2000. The importance of the recognition of distinct subgroups within the cutaneous lipophilic yeasts when evaluating their antifungal susceptibility and their role in disease is discussed. The importance of the recognition of distinct subgroups within the cutaneous lipophilic yeasts when evaluating their antifungal susceptibility and their role in disease is discussed. Oral treatment resulted in no significant suppression of cutaneous M. furfur populations with the exception of a single subgroup (A), which was reduced to undetectable levels on the skin of eight of 10 patients receiving oral terbinafine. Unable to load your delegates due to an error Unable to load your collection due to an error If there's any doubt, he or she may take skin scrapings from the infected area and view them under a microscope. 1997 Apr;31(4):445-56. doi: 10.1177/106002809703100412.Indian J Dermatol. The clinical response of the terbinafine group was also significantly higher than in the griseofulvin group. 1999 Jun;40(6 Pt 2):S31-4. 2002 Apr;40(4):1363-7. doi: 10.1128/jcm.40.4.1363-1367.2002.Sugita T, Suto H, Unno T, Tsuboi R, Ogawa H, Shinoda T, Nishikawa A.J Clin Microbiol. 2016 Sep-Oct;61(5):529-33. doi: 10.4103/0019-5154.190120.Kokollari F, Daka A, Blyta Y, Ismajli F, Haxhijaha-Lulaj K.Med Arch. 2003 Mar;21(3):234-8. doi: 10.1016/s0924-8579(02)00362-x.Di Silverio A, Mosca M, Brandozzi G, Vignoli GP, Gatti M, Gabba P, Ubezio S.G Ital Dermatol Venereol. This site needs JavaScript to work properly. 2002 Apr;40(4):1363-7. doi: 10.1128/jcm.40.4.1363-1367.2002.Sugita T, Suto H, Unno T, Tsuboi R, Ogawa H, Shinoda T, Nishikawa A.J Clin Microbiol. Preparations of terbinafine hydrochloride (maximum 1%) can be sold to the public for use in those over 16 years for external use for the treatment of tinea pedis as a cream in a pack containing maximum 15 g, or for the treatment of Malassezia furfur, the fungus causing pityriasis versicolor, has been reported to be sensitive to terbinafine in vitro but although topical therapy is effective in the treatment of pityriasis versicolor, oral therapy is not. 2009 Feb;21(1):18-26. doi: 10.5021/ad.2009.21.1.18. 2000 Aug;44(8):2185-6. doi: 10.1128/aac.44.8.2185-2186.2000. Name must be less than 100 characters 2005 Feb;6(2):165-78. doi: 10.1517/14656566.6.2.165.Jang SJ, Lim SH, Ko JH, Oh BH, Kim SM, Song YC, Yim SM, Lee YW, Choe YB, Ahn KJ.Ann Dermatol. Several studies have documented the high activity of terbinafine (Lamisil) cream in the treatment of pityriasis versicolor, with cure rates of 79-100% after 2-4 weeks of treatment. 2005 Feb;6(2):165-78. doi: 10.1517/14656566.6.2.165.Jang SJ, Lim SH, Ko JH, Oh BH, Kim SM, Song YC, Yim SM, Lee YW, Choe YB, Ahn KJ.Ann Dermatol. These patches may be lighter or darker in color than the surrounding skin and most commonly affect the trunk and shoulders.
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