Extraction was performed under local anaesthesia as no more than 3 teeth per visit were extracted. Clopidogrel tablets are contraindicated in patients with hypersensitivity (e.g., anaphylaxis) to clopidogrel or any component of the product [see Adverse Reactions (6.2)] . Ask your doctor or pharmacist for information about Plavix that was written for healthcare professionals.For more information, go to www.sanofi-aventis.us or www.bms.com or call 1-800-321-1335.Tablet: hydrogenated castor oil, hydroxypropylcellulose, mannitol, microcrystalline cellulose, polyethylene glycol 6000Film coating: ferric oxide, hypromellose 2910, lactose monohydrate, titanium dioxide, triacetin, Carnauba waxAll MedLibrary.org resources are included in as near-original form as possible, meaning that the information from the original provider has been rendered here with only typographical or stylistic modifications and not with any substantive alterations of content, meaning or intent. Avoid concomitant use of Plavix with omeprazole or esomeprazole because both significantly reduce the antiplatelet activity of Plavix Thienopyridines, including Plavix, increase the risk of bleeding.Thienopyridines inhibit platelet aggregation for the lifetime of the platelet (7–10 days). People who are treated with a stent, and stop taking Plavix too soon, have a higher risk of getting a blood clot on the stent, having a heart attack, or dying. People who are poor metabolizers at CYP2C19 will have a poor response to Plavix.
Initiating Plavix without a loading dose will delay establishment of an antiplatelet effect by several days Plavix is contraindicated in patients with active pathological bleeding such as peptic ulcer or intracranial hemorrhage.Plavix is contraindicated in patients with hypersensitivity (e.g., anaphylaxis) to clopidogrel or any component of the product Clopidogrel is a prodrug. No other difference in the rate of adverse events (other than bleeding) was reported.All MedLibrary.org resources are included in as near-original form as possible, meaning that the information from the original provider has been rendered here with only typographical or stylistic modifications and not with any substantive alterations of content, meaning or intent. Tablets are provided as follows:Store at 25° C (77° F); excursions permitted to 15°–30° C (59°–86° F) [see USP Controlled Room Temperature].Ask patients to list all prescription medications, over-the-counter medications, or dietary supplements they are taking or plan to take, including prescription or over-the-counter proton pump inhibitors (e.g., omeprazole), warfarin or NSAIDs Read this Medication Guide before you start taking Plavix and each time you get a refill.
Do not take Plavix for a condition for which it was not prescribed. This Medication Guide does not take the place of talking with your doctor about your medical condition or your treatment.Call your doctor right away if you have any of these signs or symptoms of bleeding:Do not stop taking Plavix without talking to the doctor who prescribes it for you. It is possible, but very rare, to have a stroke caused by bleeding in the brain, and blood thinners like Plavix (clopidogrel) could make the bleeding worse. In patients without such a history, the incidence of stroke was 0.9% (0.2% ICH) and 1.0% (0.3% ICH) with Effient and clopidogrel, respectively. Plavix package insert. Do not give Plavix to other people, even if they have the same symptoms that you have.
In CURE, Plavix use with aspirin was associated with an increase in major bleeding (primarily gastrointestinal and at puncture sites) compared to placebo with aspirin (see The overall incidence of bleeding is described in Table 1. Plavix helps to prevent platelets from sticking together and forming a clot that can block an artery.It is not known if Plavix is safe and effective in children.Tell all of your doctors and your dentist that you are taking Plavix. Know the medicines you take. Menu.
PACKAGE INSERT TEMPLATE FOR CLOPIDOGREL TABLET Brand or Product Name [Product name] Tablet 75mg [Product name] Tablet 300mg Name and Strength of Active Substance(s) Clopidogrel hydrogen sulphate/ bisulfate …mg equivalent to 75mg clopidogrel Clopidogrel hydrogen sulphate/ bisulfate …mg equivalent to 300mg clopidogrel Product Description [Visual … The metabolism of clopidogrel to its active metabolite can be impaired by genetic variations in CYP2C19 The metabolism of clopidogrel can also be impaired by drugs that inhibit CYP2C19, such as omeprazole or esomeprazole. TTP is a serious condition that requires urgent treatment including plasmapheresis (plasma exchange). Plavix (clopidogrel bisulfate) 75 mg tablets are available as pink, round, biconvex, film-coated tablets debossed with “75″ on one side and “1171″ on the other.
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