Theophylline clearance is reduced in patients older than 60 years old, resulting in increased serum theophylline concentrations at a given dose. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. If you miss a dose of Quibron-T, skip the missed dose and go back to your regular dosing schedule. "theophylline, anhydrous 300 MILLIGRAM in 1 TABLET" Quibron 300 (guaifenesin / theophylline) alcohol/food interactions. Cardiovascular disorders and respiratory collapse, leading to shock, cyanosis and death follow gross overdosages.Treatment: Charcoal hemoperfusion is the most effective method of extracorporeal removal, increasing theophylline clearance up to 6-fold, but serious complications may occur. Quibron T SR drug manufacturers and companies such as Bristol-Myers Squibb; Monarch Pharmaceuticals. Side effects: nausea, vomiting, headache, and insomnia. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. Any use of Quibron-T needs to heed warnings surrounding the following: The relevance of a particular drug interaction to a specific individual is difficult to determine. Some of the precautions need to be noted when considering Quibron-T for use in particular situations such as the following: Theophylline(Aquaphyllin) generic is a bronchodilator, prescribed for asthma, chronic bronchitis, emphysema, and other lung diseases. The inactive ingredients contained in Quibron-T are: Applies to: Seizures, Head Injury, Cerebral Vascular DisorderThe use of theophyllines is considered by some manufacturers to be contraindicated in patients with underlying seizure disorders unless they are receiving adequate anticonvulsant therapy. Quibron T SR active ingredients, usages, indications, composition, dosages and other pharmaceutical product information. Patients >60 years old are at the greatest risk for severe toxicity and mortality after chronic overdosage. Be sure to always carry appropriate rescue medicine (eg, bronchodilator inhaler) with you in case of an asthma attack. It works by relaxing the muscle around the airways in the lungs. Applies to: Congestive Heart Failure, Pulmonary Edema, Cor Pulmonale, Liver Disease, Shock, Influenza, Fever, Hypothyroidism, PanhypopituitarismCertain conditions have been identified as causes of reduced theophylline clearance. Induction of anesthesia with ketamine in patients receiving theophylline has been reported to produce seizures.Lithium: Theophylline increases renal clearance of lithium, so the dose of lithium may have to be increased.Pancuronium: Larger doses of pancuronium may be required due the antagonism of the drug’s effects by theophylline.Effect of Other Drugs on Theophylline Serum Concentration Measurements: Cefazolin and cephalothin may interfere with certain HPLC theophylline assays.
Therapy with theophyllines should be administered cautiously in such patients. Therapy with theophyllines should be administered cautiously in patients with impaired renal function. diazepam, 0.1 to 0.3 mg/kg up to 10 mg. Monitor vital signs, maintain blood pressure and provide adequate hydration.Postseizure Coma: Maintain airway and oxygenation. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Seizures associated with serum theophylline concentrations >30 µg/mL are often resistant to anticonvulsant therapy and may result in irreversible brain injury if not rapidly controlled. Safe use in pregnancy has not been established relative to possible adverse effects on fetal development, but neither has adverse effects on fetal development been established. In general, the drug is metabolized sufficiently rapidly so as not to warrant consideration of dialysis.Dosage should be calculated on the basis of ideal body weight.
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