Agitation includes combativeness, hyperactivity, disinhibition, wandering, and restlessness. Risperidone appears effective in controlling agitation in patients with dementia and has a relatively benign adverse-effect profile, but more clinical trials are needed to elucidate its role for this indication. See full prescribing information for complete boxed warning. 2012 Jun 8;12:72. doi: 10.1186/1471-2288-12-72.Lukas A, Schuler M, Fischer TW, Gibson SJ, Savvas SM, Nikolaus T, Denkinger M.Z Gerontol Geriatr. Unable to load your collection due to an error This site needs JavaScript to work properly.
Doses have varied among studies.
2005 Oct;107(6):497-508. doi: 10.1016/j.clineuro.2005.03.013.Katz I, de Deyn PP, Mintzer J, Greenspan A, Zhu Y, Brodaty H.Int J Geriatr Psychiatry. COVID-19 is an emerging, rapidly evolving situation. Risperdal (Risperidone) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. 2007 May;22(5):475-84. doi: 10.1002/gps.1792.Brodaty H, Ames D, Snowdon J, Woodward M, Kirwan J, Clarnette R, Lee E, Lyons B, Grossman F.J Clin Psychiatry. Silverchair Information Systems Unable to load your delegates due to an error
Risperidone for psychosis of Alzheimer's disease and mixed dementia: results of a double-blind, placebo-controlled trial. A low initial dosage that is gradually adjusted upward is recommended. 2007 Apr-Jun;1(2):190-195. doi: 10.1590/s1980-57642008dn10200012.Genes Dev. 2012 Jun 25;12:31. doi: 10.1186/1471-2318-12-31.BMC Med Res Methodol.
2007 Nov;15(11):942-52. doi: 10.1097/JGP.0b013e3180cc1ff5. eCollection 2015.Gordon AL, Logan PA, Jones RG, Forrester-Paton C, Mamo JP, Gladman JR; Medical Crises in Older People Study Group.BMC Geriatr. A low initial dosage that is gradually adjusted upward is recommended. The injectable version is long-acting and lasts for about two weeks. Epub 2012 May 11.Psychiatry Investig.
2004 Aug 13;3(1):3. doi: 10.1186/1472-6955-3-3. Risperidone appears effective in controlling agitation in patients with dementia and has a relatively benign adverse-effect profile, but more clinical trials are needed to elucidate its role for this indication. Traditional neuroleptics have been the mainstay of treatment for agitated behavior in persons with dementia, but these agents have limited efficacy and are associated with high rates of adverse effects, including worsening of already poor cognitive functioning. This antipsychotic medication is sometimes recommended to treat agitation, hallucination, and other symptoms of distress associated with dementia in older adults. Clipboard, Search History, and several other advanced features are temporarily unavailable. doi: 10.1002/14651858.CD002852.Pollock BG, Mulsant BH, Rosen J, Mazumdar S, Blakesley RE, Houck PR, Huber KA.Am J Geriatr Psychiatry. Epub 2011 Nov 4.BMC Nurs. Risperidone for the elderly can be accompanied by an increased risk of stroke if it is not used with care. Unable to load your collection due to an error
Dementia affects up to 70% of nursing-home patients, and more than 90% of them exhibit aggressive or agitated behavior or severe depression. Wiley Risperidone may also be useful for treating acute agitation in patients with a high risk of EPS and for long-term treatment of "sundowning" (agitation and confusion starting in the late afternoon and worsening at night).
2000 Sep;23(3):183-95. doi: 10.2165/00002018-200023030-00002.Cochrane Database Syst Rev. Mary McMahon Last Modified Date: August 08, 2020 .
Risperidone: a review of its use ... vascular dementia or mixed dementia, risperidone 1 mg/day was at least as effective as haloperidol and superior to placebo, ... Risperidone, administered at a low dosage of 1 mg/day was associated with fewer extrapyramidal symptoms compared with haloperidol in … This site needs JavaScript to work properly. Patients stabilised on oral risperidone for at least 2 wk in doses >4 mg daily: 37.5 mg every 2 wk.
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