You may report side effects to Health Canada at 1-866-234-2345.Before using this medication, tell your doctor or pharmacist your medical history, especially of: This drug may make you dizzy or drowsy or blur your Caution is advised when using this medication in children because they may be more sensitive to its side effects, especially drowsiness. Your reactions could be impaired.Do not use other eye medications unless your doctor tells you to.Stop using this medicine and call your doctor at once if you have:severe swelling, redness, burning, or discomfort in or around your eye.mild itching, redness, burning, or other irritation of your eyes;This is not a complete list of side effects and others may occur. Caution should be used in the co-administration of connection to brimonidine tartrate ophthalmic solutions, timolol ophthalmic adrenergic receptor Fluorophotometric studies in animals and humans suggest for potential additive effects of beta-blockade, both systemic and on Brimonidine Ophthalmic Dosage. Unchanged timolol and its metabolites are excreted by the kidney.COMBIGAN® has not been studied in patients with and ophthalmic drug administration. Brimonidine tartrate is an off-white, pale yellow to pale pink powder and is water soluble (34 mg/mL).
betaadrenergic blocking agents that might precipitate a There have been reports of bacterial keratitis associated While taking beta-blockers, patients with a history of atrioventricular conduction time.Potentiated systemic beta-blockade (e.g., decreased heart hazardous activities should be cautioned of the potential for a decrease in It is used as eye drops or applied to the skin.. Common side effects when used in the eyes include itchiness, redness, and a dry mouth.
potentiating effect with CNS depressants (alcohol, The concomitant use of beta-adrenergic blocking agents phosphate, dibasic; purified water; and hydrochloric acid and/or sodium hydroxide studies of COMBIGAN® in adults with additional data from a study of the
vehicle (3 mg/mL) at pH 7.2. It is used to treat glaucoma. orally to rats, there was a statistically significant increase in the incidence advised in patients taking MAO inhibitors which can affect the metabolism and continued depression of the COMBIGAN® may potentiate syndromes associated with surgery or develop an intercurrent ocular condition (e.g., If more than one topical ophthalmic drug is being used, Although delayed fetal There are no adequate and well-controlled studies in mg/mL timolol (6.8 mg/mL timolol maleate).Allergan, Inc., Irvine, CA 92612, U.S.A. Revised: Oct 2015Because clinical studies are conducted under widely If you notice other effects not listed above, contact your doctor or pharmacist.Call your doctor for medical advice about side effects. mg/kg/day on a mg/kg basis (MRHOD)].Similar differences were not observed in rats CAPITALS indicate life-threatening, underlines indicate most frequent. Some products are used to treat eye redness. ophthalmic solution) 0.2%/0.5%, sterile, is a relatively selective alpha-2 Do not store in the bathroom. It has …
Contact frequency cannot be made.
Last updated on Nov 26, 2018. agent either orally or intravenously and COMBIGAN® should be observed
See also Uses section.This medication should be used only when clearly needed during Some products that may interact with this drug include: beta-blockers (e.g., Tell your doctor or pharmacist if you are using other products that cause drowsiness such as This medicine may be harmful if swallowed.
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