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If you notice other effects not listed above, contact your doctor or pharmacist.Call your doctor for medical advice about side effects. TENORMIN® (atenolol), a synthetic, beta 1-selective (cardioselective) adrenoreceptor blocking agent, may be chemically described as benzeneacetamide, 4-[2'-hydroxy-3'- [(1 methylethyl)amino]propoxy]-.The molecular and structural formulas are: C 14 H 22 N 2 O 3. However, as has been shown for all beta-blocking agents, the antihypertensive effect does not appear to be related to plasma level.Consistent with its negative chronotropic effect due to beta blockade of the SA node, atenolol increases sinus cycle length and sinus node recovery time. The dose range of atenolol is narrow and increasing the dose beyond 100 mg once daily is not associated with increased antihypertensive effect. Several possible mechanisms have been proposed and include: (1) competitive antagonism of catecholamines at peripheral (especially cardiac) adrenergic neuron sites, leading to decreased cardiac output, (2) a central effect leading to reduced sympathetic outflow to the periphery, and (3) suppression of renin activity. *Based on the maximum dose of 100 mg/day in a 50 kg patient.Neonates born to mothers who are receiving Atenolol Tabletsat parturition or breast-feeding may be at risk for hypoglycemia and bradycardia. The mechanisms of the antihypertensive effects of beta-blocking agents have not been established. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.Things to remember when you fill your prescription.WebMD does not provide medical advice, diagnosis or treatment.This survey is being conducted by the WebMD marketing sciences department.All information will be used in a manner consistent with the WebMD Additionally, common effects associated with overdosage of any beta-adrenergic blocking agent and which might also be expected in Atenolol Tablets overdose are congestive heart failure, hypotension, bronchospasm and/or hypoglycemia.Treatment of overdose should be directed to the removal of any unabsorbed drug by induced emesis, gastric lavage, or administration of activated charcoal. The maximum early effect on exercise tolerance occurs with doses of 50 to 100 mg, but at these doses the effect at 24 hours is attenuated, averaging about 50% to 75% of that observed with once a day oral doses of 200 mg.In patients who tolerate the full intravenous dose (10 mg), Atenolol Tablets 50 mg should be initiated 10 minutes after the last intravenous dose followed by another 50 mg oral dose 12 hours later. Atenolol, in addition to its effects on survival, has shown other clinical benefits including reduced frequency of ventricular premature beats, reduced chest pain, and reduced enzyme elevation.Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. In refractory cases, a transvenous cardiac pacemaker may be indicated.HEART BLOCK (SECOND OR THIRD DEGREE): Isoproterenol or transvenous cardiac pacemaker.CARDIAC FAILURE: Digitalize the patient and administer a diuretic. When renal function is impaired, elimination of atenolol is closely related to the glomerular filtration rate; significant accumulation occurs when the creatinine clearance falls below 35 mL/min/1.73mA significant beta-blocking effect of atenolol, as measured by reduction of exercise tachycardia, is apparent within one hour following oral administration of a single dose. If bradycardia or hypotension requiring treatment or any other untoward effects occur, Atenolol Tabletsshould be discontinued. If it is near the time of the next dose, skip the missed dose.

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