0000060895 00000 n Pancreatic cancer by the numbers. 2008, 113 (4): 870-878. When the sample was divided into those with and without MDE, the groups only differed with regard to serum IL-6 levels. 0000068497 00000 n
0000098695 00000 n Cancer. Pancreatic cancer often goes undetected until it's advanced and difficult to treat. 2009, 37 (4): 613-621. But after witnessing her husband Peter’s unexplained psychological distress preceding his diagnosis with a pancreatic neuroendocrine tumor (PNET), she scoured scientific and clinical literature to determine whether changes in mental health could be an early symptom of pancreatic cancer. 0000049474 00000 n This is … 0000110008 00000 n 0000015287 00000 n 0000006443 00000 n 10.1007/s00520-006-0194-7.Auret KA, Schug SA, Bremner AP, Bulsara M: A randomized, double-blind, placebo-controlled trial assessing the impact of dexamphetamine on fatigue in patients with advanced cancer. Psychooncology. Cancer. 10.1093/jncimonographs/lgh014. Psychooncology. 0000079778 00000 n Several of them described a strong relationship between depression and mortality and some could not detect a linkage at all. Add it all together and it’s no wonder depression often precedes a cancer diagnosis. Br J Cancer. To address this issue we reviewed published data on pancreatic cancer related depression for evidence of a relationship between psychological distress and the course of this disease.A comprehensive study by Hinz et al. 0000102587 00000 n - Second, is depression itself a promoter of tumor development or are pathophysiological changes due to cancer responsible for the high incidence of depression?One possible approach to the evident bidirectional relationship between depression and pancreatic cancer is to regard the extent of psychological distress patients experience being faced with such fatal diagnosis. 10.1016/S0895-4356(99)00022-0.Derogatis LR, Morrow GR, Fetting J, Penman D, Piasetsky S, Schmale AM, Henrichs M, Carnicke CL: The prevalence of psychiatric disorders among cancer patients. After completing the chemoradiotherapy stage, 34 of the 49 of the clinical trial participants were able to have their tumors removed, with 30 of those procedures successfully eliminating all evidence of cancer around the tumor. Animal models indicate that proinflammatory cytokines can elicit "depression-like" symptoms [Depression is one of the crucial factors impairing life quality of cancer patients. Get the latest news and updates from the Pancreatic Cancer Action Network. 1971, 221: 120-127. Prog Neuropsychopharmacol. 0000027914 00000 n J Abnorm Psychol. JAMA.
0000110297 00000 n 0000002792 00000 n J Pain Symptom Manage. Gen Hosp Psychiatry. All the authors read and approved the final manuscript.This article is published under license to BioMed Central Ltd. 2008, 62 (1): 75-83.
The drugs are known as angiotensin-receptor blockers and include medicines such as telmisartan (), losartan (Cozaar, Hyzaar), valsartan and candesartan (). Pancreatic Cancer Action Network®, PanCAN®, PurpleStride®, Wage Hope®, Know Your Tumor®, Powerful Knowledge. 10.1192/bjp.115.528.1277.Steel JL, Geller DA, Gamblin TC, Olek MC, Carr BI: Depression, immunity, and survival in patients with hepatobiliary carcinoma. Most of the studies demonstrate strikingly high incidence rates of depression in cancer patients particularly among those with fatal prognosis like pancreatic cancer. 2001, 10 (1): 19-28. 2002, 325 (7372): 1066-10.1136/bmj.325.7372.1066.Coyne JC, Palmer SC: More claims about depression, immune function, and survival that exceed the evidence. 2001, 158 (8): 1252-1257. Part of
Semin Clin Neuropsychiatry. 2003, 65 (5): 884-888. 10.1200/JCO.2005.02.3259.Group RFA: A position paper: Screening key indicators in cancer patients--Pain as a 5th vital sign and emotional distress as a 6th vital sign. Support Care Cancer. 0000018326 00000 n
1995, 52 (2): 89-99.Carlson LE, Angen M, Cullum J, Goodey E, Koopmans J, Lamont L, MacRae JH, Martin M, Pelletier G, Robinson J, et al: High levels of untreated distress and fatigue in cancer patients.
2009, 18 (1): 1-5. 2007, 8 (2): 240-253.Petitto JM, Evans DL: Treatment of Depression in Individuals With Cancer: Implications of Antidepressant Pharmacotherapy. 2004, 13 (5): 359-363.
0000029991 00000 n Psychooncology. Pancreatic cancer and depression. A new treatment combination – combining chemotherapy and radiation therapy with a common blood pressure drug – has shown promise in an early-phase clinical trial for patients with locally-advanced pancreatic cancer.. 0000057123 00000 n J Clin Oncol.
0000064731 00000 n
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