2016 Apr-Jun;10(2):88-91. doi: 10.1016/j.dsx.2015.09.021. Acarbose works by slowing the action of certain chemicals that break down food to release glucose (sugar) into your blood. Wang Z, Sun J, Han R, Fan D, Dong X, Luan Z, Xiang R, Zhao M, Yang J.Diabetes Obes Metab. 2020 Jan;11(1):247-257. doi: 10.1007/s13300-019-00742-8. The tendency of acarbose to promote weight loss is shared by long-lasting GLP-1 receptor mimics currently used in diabetes therapy; indeed, these agents can aid weight loss in non-diabetics as well.66, 67 Hence, it is reasonable to suspect that GLP-1 is a mediator of the favourable impact of acarbose therapy on weight control.
2020 Feb 7;6(3):313-323. doi: 10.1002/osp4.405. Flowchart of trial selection in the systematic review and network meta-analysis.
Acarbose is used (with diet only or diet and other medications) to treat type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood) . 13 Overweight and obesity are associated with a host of health problems related to mechanical and metabolic stresses, including osteoarthritis, type … Free PMC article Acarbose was superior to DPP-4is regarding weight loss (MD -1.23 kg, -2.08 to -0.33). Frontiers Media SA
Flowchart of trial selection in the systematic review and network meta-analysis. Name must be less than 100 characters Higher baseline HbA1c levels and lower decreases from baseline in fasting plasma glucose (FPG) levels after 48 weeks of treatment were negatively associated with losing ≥ 2 kg of weight … Pair-wise meta-analysis for comparisons between acarbose and dipeptidyl peptidase-4 inhibitors in Network plots, network meta-analysis comparisons, and rank probabilities among acarbose, dipeptidyl peptidase-4 inhibitors, metformin, pioglitazone, and placebo in Comparisons among acarbose, dipeptidyl peptidase-4 inhibitors, metformin, pioglitazone, and placebo in network meta-analysis in doi: 10.1002/14651858.CD003639.pub2.Diabetes Obes Metab. Elsevier Science
This can lead to a cascade of disordered metabolic signaling that culminates in diseases such as diabetes and cardiovascular disease. Copyright © 2020 Zhang, Xu, Tang, Pan and Tong. Epub 2016 Feb 2.
2016 May-Jun;30(4):628-37. doi: 10.1016/j.jdiacomp.2016.01.023. Unable to load your delegates due to an error 2018 Nov 22;10(12):1821. doi: 10.3390/nu10121821. There was a small weight loss in both treatment groups (acarbose 1.1kg, placebo 0.8kg) which was also significant for acarbose (P=0.042). Results: In patients treated with acarbose, males were less likely than females to lose ≥ 2 kg of weight (p = 0.025). doi: 10.1016/j.jdiacomp.2016.01.023.
doi: 10.1002/14651858.CD011798.pub2.Cochrane Database Syst Rev. Frontiers Media SA Animal studies with acarbose have consistently shown that acarbose has a body weight-lowering action. This is also reflected in the BMI data . COVID-19 is an emerging, rapidly evolving situation. Epub 2017 May 22.Holmbäck U, Forslund A, Grudén S, Alderborn G, Söderhäll A, Hellström PM, Lennernäs H.Obes Sci Pract.
Published by Elsevier Inc. Unable to load your delegates due to an error miglitol, acarbose, and voglibose, by virtue of better weight management and specific loss of visceral fat, should contribute to net general reduction of CV risk factors (see below) and CV risk. Acarbose as an aid to Weight Loss.
COVID-19 is an emerging, rapidly evolving situation. 2005 Apr 18;(2):CD003639. Consistent data demonstrate that acarbose induces weight loss in animals.130 The data in humans are more ambiguous; some reports indicate that acarbose is weight-neutral,85, 131, 132 while others report significant weight loss. Acarbose had more withdrawal, gastrointestinal, and overall adverse events than DPP-4is (p < 0.05), but the differences disappeared after longer treatment (p > 0.05). Epub 2014 Oct 12.Talaviya PA, Saboo BD, Dodiya HG, Rao SK, Joshi SR, Modh VB, Ghadiya SV.Diabetes Metab Syndr.
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