Only articles of high quality directly pertaining to the safety and efficacy of topical mometasone furoate of various formulations in relation to other corticosteroids in the treatment of psoriasis, eczema, atopic dermatitis and seborrhoeic dermatitis were included. Mometasone furoate exhibits anti‐inflammatory, anti‐pruritic and vasoconstrictive properties.The precise mechanism by which corticosteroids exert their anti‐inflammatory effect is unknown.
Cl, chlorine. 1991 Dec;25(6 Pt 2):1149-52. doi: 10.1016/0190-9622(91)70314-r.Menter A, Abramovits W, Colón LE, Johnson LA, Gottschalk RW.Med J Armed Forces India. Abstracts and studies relating to allergic contact dermatitis, vitiligo, phimosis, acute radiation dermatitis, lichen sclerosus, melasma, chronic idiopathic urticaria and alopecia areata were not included.Mometasone furoate (9α,21‐dichloro‐11β,17α –dihydroxy‐16α‐methyl‐pregna‐1,4‐diene‐3,20‐dione‐17‐(2′) furoate) is the 17‐ester of the 16α‐methyl analogue of beclomethasone (Fig. 1998 Jul;11(1):19-24.J Am Acad Dermatol. betamethasone and clobetasol. Topical corticosteroids have been extensively used for over 30 years to treat various inflammatory skin conditions. Both drugs were shown to be highly effective and were well tolerated. In clinical trials, mometasone furoate shows comparable or significantly better efficacy, depending on the comparator, in all indications studied in both adults and children. Eczema in children can usually be managed using hydrocortisone and clobetasone.
Clobetasol and triamcinolone 0.1% are generally utilized for skin disease on the body, whereas desonide is the appropriate choice for skin disorders on the face, groin, axillae, and breasts. Different brands containing the same corticosteroid at the same concentration may still vary in potency. Properly used hydrocortisone or clobetasone do not damage the skin, even when applied to a childs face.For severe exacerbations clobetasone may need to be applied for a short period, before weaning down to hydrocortisone. High potency: amcinonide (Cylocort), desoximetasone (Topicort, Topicort LP), halcinonide (Halog), and triamcinolone acetonide (Kenalog). Secondly, emphasise that all steroids are not of the same potency: clobetasone (Eumovate) is five times more potent than hydrocortisone and betamethasone (Betnovate) is five times more potent than clobetasone, and clobetasol (Dermovate) is more potent again. In clinical trials the efficacy of mometasone furoate 0.1% ointment, cream and lotion applied once daily to patients with a variety of inflammatory skin conditions including psoriasis, eczema, atopic dermatitis and seborrhoeic dermatitis for between 2–12 weeks, was found to be significantly superior to twice‐daily applications of less potent corticosteroids of similar formulations, and it was comparable to or significantly superior to that of several other highly potent corticosteroids of a similar formulation that required application twice or thrice daily, regardless of the patients’ age.Although mometasone furoate 0.1% demonstrates greater anti‐inflammatory activity and a longer duration of action than betamethasone relative to other topical corticosteroids with a similar or weaker potency, topical formulations of mometasone furoate 0.1% have been shown to be associated with a low risk of corticosteroid‐related adverse events, such as skin atrophy and other local events, and to have a very limited potential to induce systemic adverse effects, including hypothalamic‐pituitary‐adrenal axis suppression.Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. There are a large number of topical steroids available. Steroids, therefore, represent a very logical treatment option for this condition. Reprieves were short-lived. It is well tolerated with only transient, mild to moderate local adverse effects. A review of its pharmacological properties and therapeutic use in the treatment of dermatological disordersBioequivalence of 0.1% mometasone furoate lotion to 0.1% mometasone furoate hydrogelMometasone furoate: a well‐established topical corticosteroid now with improved galenic formulationsPercutaneous absorption of 0.1% mometasone furoate ointment fate, excretion and adrenocortical suppressionComparison of the local and systemic side effects of methylprednisolone aceponate and mometasone furoate applied as ointments with equal antiinflammatory activityRandomized crossover comparison of adrenal suppressive effects of dermal creams containing glucocorticosteroidsComparison of the effect of mometasone furoate ointment 0.1% and hydrocortisone ointment 1% on adrenocortical function in psoriasis patientsContinuous and intermittent treatment of atopic dermatitis in adults with mometasone furoate versus hydrocortisone 17‐butyrateComparison of mometasone furoate 0.1% cream and hydrocortisone 1.0% cream in the treatment of childhood atopic dermatitisMometasone furoate in the treatment of atopic dermatitis in childrenComparison of skin atrophy and vasoconstriction due to mometasone furoate, methylprednisolone and hydrocortisoneTopical mometasone furoate and betamethasone‐17‐valerate decrease collagen synthesis to a similar extent in human skin Mometasone furoate ointment and cream 0.1 percent in treatment of psoriasis: comparison with ointment and cream formulations of fluocinolone acetonide 0.025 percent and triamcinolone acetonide 0.1 percentEfficacy and safety of mometasone furoate 0.1% once daily versus fluticasone propionate 0.005% twice daily in the management of psoriasisA comparative study of mometasone furoate ointment and betamethasone valerate ointment in patients with psoriasis vulgarisA clinical investigation of the efficacy and safety of mometasone furoate ointment 0.1% Comparison of mometasone furoate 0.1% ointment and betamethasone dipropionate 0.05% ointment in the treatment of psoriasis vulgarisComparative study of mometasone furoate and betamethasone dipropionate in the treatment of atopic dermatitisEffect of duration of application and dosing frequency on the efficacy of topical 0.1% mometasone furoate ointment in psoriasisOnce daily 0.1% mometasone furoate cream versus twice daily 0.1% betamethasone valerate in the treatment of a variety of dermatosesMometasone versus betamethasone cream: a trial in dermatosesClinical study of mometasone furoate cream 0.1% compared to hydrocortisone butyrate cream 0.1% in treatment of atopic and seborrheic dermatitisHydrocortisone butyrate 0.1% cream in the treatment of chronic dermatitisThe therapeutic efficacy of mometasone furoate cream 0.1%, applied once daily A comparison of once daily application of mometasone furoate 0.1% cream compared with twice daily hydrocortisone valerate 0.2% cream in pediatric atopic dermatitis who failed to respond to hydrocortisoneComparison of the safety and efficacy of mometasone furoate cream 0.1% and clobetasone butyrate cream 0.05% in the treatment of children with a variety of dermatosesLong term, intermittent treatment of chronic hand eczema with mometasone furoateAn open study of efficacy and safety of long term treatment with mometasone furoate fatty cream in the treatment of adult patients with atopic dermatitisA novel formulation of mometasone furoate in psoriasis patients: a multicenter, randomized, double‐blind clinical studyBioavailability, antipsoriatic efficacy and tolerability of a new light cream with mometasone furoate 0.1%Efficacy and patient‐reported outcomes of a new mometasone cream treating atopic eczemaMometasone furoate lotion once daily versus triamcinolone acetonide lotion twice daily in psoriasisClinical trial in scalp psoriasis mometasone furoate lotion 0.1% applied once daily In situ bioadhesive film-forming system for topical delivery of mometasone furoate: Characterization and biopharmaceutical properties, Cutaneous sıde‐effects of the potential COVID‐19 drugs,
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