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For people taking over-the-counter Zantac and related medications, the FDA recommends they consider another heartburn medicine. Healthcare providers should not change their prescribing practices and patients should not change their use of these products at this time.Both drugs are used for the treatment of GERD, esophageal erosions and for maintenance of healing erosions of the esophagus. Prilosec is also sold over the counter for frequent heartburn.Audience: Gastroenterologists, other healthcare professionals, consumersThe results from the study of Prilosec and analyses from an ongoing study of Nexium raised concerns that long-term use of Prilosec or Nexium may have increased the risk of heart attacks, heart failure, and heart-related sudden death in those patients taking either one of the drugs compared to patients who received surgery. The recalled Apotex products are sold at and labeled by Walgreens, Walmart and Rite-Aid, according to the FDA. Breaking News Emails But it has not stopped selling Zantac in the U.S. These notices may include a list of possible medication recalls, market withdrawals, alerts and warnings. FDA recommends healthcare professionals, when prescribing proton pump inhibitors, should consider whether a lower dose or shorter duration of therapy would adequately treat the patient's condition.The safety communication includes a data summary with a table and references which support the epidemiological studies reviewed for this communication.Audience: Cardiovascular healthcare professionals, pharmacistsFDA notified healthcare professionals of new safety information concerning an interaction between clopidogrel (Other drugs that are expected to have a similar effect and should be avoided in combination with clopidogrel include: cimetidine, fluconazole, ketoconazole, voriconazole, etravirine, felbamate, fluoxetine, fluvoxamine, and ticlopidine. The Agency conducted a comprehensive review of the data from two studies that were submitted to FDA. While the greatest increased risk for fractures in these studies involved people who had been taking prescription proton pump inhibitors for at least one year or who had been taking high doses of the prescription medications (not available over-the-counter), as a precaution, the "Drug Facts" label on the OTC proton pump inhibitors (indicated for 14 days of continuous use) also is being revised to include information about this risk. Even so, the warning has led some pharmacies and manufacturers to stop selling drugs containing Zantac's active ingredient, ranitidine. The FDA Alert(s) below may be specifically about omeprazole or relate to a group or class of drugs which include omeprazole.MedWatch Safety Alerts are distributed by the FDA and published by Drugs.com. It is a weak base, freely soluble in ethanol and methanol, and slightly soluble in acetone and isopropanol and very slightly soluble in water. Walgreens earlier said it's removing Zantac products from shelves while the FDA continues its investigation. See the "Update of Safety Review" for information regarding the two studies that were reviewed.The results from the study of Prilosec and analyses from an ongoing study of Nexium raised concerns that long-term use of Prilosec or Nexium may have increased the risk of heart attacks, heart failure, and heart-related sudden death in those patients taking either one of the drugs compared to patients who received surgery. Several drugs also treat heartburn and other stomach conditions. Following is a list of possible medication recalls, market withdrawals, alerts and warnings.

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