Br J Clin Pract 43 (1989): 79-8155. Clin Cardiol 14 (1991): 165-831. Rosenberg L, Shapiro S, Slone D, Kaufman DW, Miettinen OS, Stolley PD "Thiazides and acute cholecystitis." Ann Intern Med 119 (1993): 8605. Fager G, Berglund G, Bondjers G, Elmfeldt D, Lager I, Olofsson SO, Smith U, Wiklund O "Effects of anti-hypertensive therapy on serum lipoproteins.

There is hypervolemia during normal pregnancy which is not harmful to either the fetus or the mother (in the absence of cardiovascular disease) but which is associated with edema, including generalized edema, in the majority of pregnant women. JAMA 215 (1971): 480-280. Papademetriou V, Fletcher R, Khatri IM, Freis ED "Diuretic-induced hypokalemia in uncomplicated systemic hypertension: effect of plasma potassium correction on cardiac arrhythmias." Pickkers P, Schachter M, Hughes AD, Feher MD, Sever PS "Thiazide-induced hyperglycaemia: a role for calcium-activated potassium channels?"

Thiazides are eliminated rapidly by the kidney.In the management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension.As adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Harper R, Ennis CN, Heaney AP, Sheridan B, Gormley M, Atkinson AB, Johnston GD, Bell PM "A comparison of the effects of low- and conventional-dose thiazide diuretic on insulin action in hypertensive patients with NIDDM." Oral Cytoxan dosing is usually in the range of 1 to 5 mg/kg/day for both initial and maintenance dosing. Am Surg 33 (1967): 7-1171. Garratty G, Houston M, Petz LD, Webb M "Acute immune intravascular hemolysis due to hydrochlorothiazide." Insulin requirements in diabetic patients may be increased, decreased, or unchanged. This diminution is not sufficient to preclude effectiveness of the pressor agent for therapeutic use. N Engl J Med 303 (1980): 546-820. Knowles SR, Wong GA, Rahim SA, Binkley K, Phillips EJ, Shear NH "Hydrochlorothiazide-induced noncardiogenic pulmonary edema: an underrecognized yet serious adverse drug reaction." Sensitivity reactions are more likely to occur in patients with a history of allergy or bronchial asthma. Fine SR, Lodha A, Zoneraich S, Mollura JL "Hydrochlorothiazide-induced acute pulmonary edema." • 50 mg capsule for oral administration contains 50 mg of cyclophosphamide USP. 2.2 Dosing for Minimal Change Nephrotic Syndrome in Pediatric Patients An oral dose of 2 mg per kg daily for 8 to 12 weeks (maximum cumulative dose 168 mg per kg) is recommended.

Associated symptoms include There are rare case reports of hydrochlorothiazide-induced immune A 53-year-old man with hypertension developed nausea, vomiting, diarrhea, and progressive anorexia and weakness associated with scleral icterus, anemia with spherocytosis, dark red urine with proteinuria, bilirubinuria, hemoglobinuria, and elevated lactic dehydrogenase levels 18 months after beginning hydrochlorothiazide (the active ingredient contained in Esidrix) and 1.

Along with its needed effects, hydrochlorothiazide (the active ingredient contained in Esidrix) may cause some unwanted effects. Kasiske BL, Ma JZ, Kalil RS, Louis TA "Effects of antihypertensive therapy on serum lipids." Holland GW "Stenosing ulcers of the small bowel associated with thiazide and potassium therapy."

Wagner W, Longerbeam JK, Smith LL, Feikes HL "Drug-induced ulcers of the small bowel causing intestinal obstruction or perforation." N Z Med J 64 (1965): 383-570. Highest known doses ingested: children, 500 mg (14-year-old girl); young children, 125 mg (2 1/2-year-old child).The most prominent feature of poisoning with Esidrix is acute loss of fluid and electrolytes.Therapy should be individualized according to patient response. Br Med J 1 (1978): 4835. In patients with renal disease, thiazides may precipitate azotemia. Onset of symptoms can occur within minutes (range 10 to 150 minutes) of first exposure to the drug. The common complications of hyperparathyroidism such as renal lithiasis, bone resorption, and peptic ulceration have not been seen. Parodi A, Romagnoli M, Rebora A "Subacute cutaneous lupus erythematosus-like eruption caused by hydrochlorothiazide."

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