Indicated to improve wakefulness in adults with excessive sleepiness associated with obstructive sleep apnea (OSA)Doses up to 400 mg/day, given as a single dose, have been well tolerated, but there is no consistent evidence that this dose confers additional benefit beyond that of the 200 mg/day doseIndicated to improve wakefulness in adults with excessive sleepiness associated with narcolepsyDoses up to 400 mg/day, given as a single dose, have been well tolerated, but there is no consistent evidence that this dose confers additional benefit beyond that of the 200 mg/day doseIndicated to improve wakefulness in adults with excessive sleepiness associated with shift work disorder (SWD)200 mg PO as a single dose ~1 hr prior to patient's work shiftOrphan designation of a fixed dose combination of modafinil and flecainide for narcolepsyRisk of skin reactions (eg SJS, toxic necrolysis, and drug rash with eosinophilia and systemic symptoms); discontinue if rash or other hypersensitivity reactions occurMay impair ability to operate heavy machinery and perform hazardous tasksNot recommended in patients with angina, cardiac ischemia, recent history of myocardial infarction, left ventricular hypertrophy, or mitral valve prolapseUse with caution in severe hepatic impairment, elderly, history of: depression, psychosis (may exacerbate psychiatric symptoms), or maniaUse with caution in patients with Tourette syndrome; stimulants may unmask ticksMay reduce effectiveness of steroidal contraceptives 1 month after discontinuation of drug therapyReassess degree of sleepiness frequently; if used adjunctively with continuous positive airway pressure (CPAP): Periodic assessment of CPAP compliance is necessaryDiscontinue therapy if symptoms suggest angioedema or anaphylaxisDiscontinue if multiorgan hypersensitivity reaction is suspectedWell controlled studies in pregnant women have not been performedIntrauterine growth restriction and spontaneous abortion have been reported with modafinil and armodafinilIn studies conducted in rats (modafinil, armodafinil) and rabbits (modafinil), developmental toxicity was observed at clinically relevant plasma exposuresPregnancy registry to collect information on pregnancy outcomes of women exposed to modafinil: 866-404-4106A: Generally acceptable.



Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. If your dose is different, do not change it unless your doctor tells you to do so. mike, 2 år sedan Svara. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem fo…
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The amount of medicine that you take depends on the strength of the medicine.

News Contact the applicable plan Controlled studies in pregnant women show no evidence of fetal risk.Unknown; not sympathomimetic; may increase dopamine levels in the brain by binding to the dopamine transporter and inhibiting dopamine reuptakeEnzymes induced: CYP1A2, CYP2B6, CYP3A4; induces its own metabolism (chronic)Adding plans allows you to compare formulary status to other drugs in the same class.To view formulary information first create a list of plans. Follow your doctor's orders or the directions on the label. backarna, så har man ju satt sig lite i den situationen själv. 高梁板に戻る 全部 最新50 1-101-201-301-401-501-601-701-801-901-1001- マンマン（・∀・）ｲｲ!! 부산교구 여성회 부산여성회(회장 : 오연화)에서는 지난해에 이어 제4기 우리옷 만들기 강좌(3.10~5.1 초급반, 10.3~10.3 중급반)와 제9회 주 provider for the most current information.The recipient will receive more details and instructions to access this offer.By clicking send, you acknowledge that you have permission to email the recipient with this information.The recipient will receive more details and instructions to access this offer.By clicking send, you acknowledge that you have permission to email the recipient with this information.

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