If too high a dose is initiated or if the dosage is increased too rapidly side effects may occur. Some may be better suited for you than others.
Not every pharmacy stocks this drug.
0000000016 00000 n 0000002116 00000 n When filling your prescription, be sure to call ahead to make sure your pharmacy carries it. Baclofen acts on the spinal cord nerves and decreases the number and severity of muscle spasms caused by multiple sclerosis or spinal cord diseases. You may report side effects to the FDA at 1-800-332-1088. trailer However, as the liver does not play a significant role in the disposition of baclofen, it is unlikely that baclofen pharmacokinetics would be altered to a clinically significant level in patients with hepatic impairment. However, baclofen has the potential of elevating liver enzymes. 322 26 The lowest dose compatible with an optimal response is recommended. You can cut or crush the tablet. Baclofen oral tablet is used for either short-term or long-term treatment. It comes with serious risks if you don’t take it as prescribed.If you think you’ve taken too much of this drug, call your doctor or local poison control center.
All rights reserved. 0000007690 00000 n These are not all of the side effects that may occur. Supportive measures and symptomatic treatment should be given for complications such as hypotension, hypertension, convulsions, gastrointestinal disorders and respiratory or cardiovascular depression.Since the drug is excreted chiefly via the kidneys, generous quantities of fluid should be given, possibly together with a diuretic. Read all information given to you. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. In most cases, the patients had additional risk factors associated with an increased risk of suicide including alcohol use disorder, depression and/or a history of previous suicide attempts. Baclofen oral tablet can interact with other medications, vitamins, or herbs you may be taking. 0000003732 00000 n These two formulations are bioequivalent. Thus, caution should be exercised when baclofen is used concomitantly with lithium.During concomitant treatment with tricyclic antidepressants, the effect of baclofen may be potentiated, resulting in pronounced muscular hypotonia. Careful titration of dosage is essential (particularly in the elderly) until the patient is stabilised. The dose may be increased slowly if required, but a maximum daily dose of more than 100 mg is not advised unless the patient is in hospital under careful medical supervision. alcohol, diazepam, tricyclic antidepressants) have been taken at the same time. The clinical relevance of these findings is not known.Experimental evidence to date suggests that baclofen does not possess either carcinogenic or mutagenic properties.Store in a dry place below 25°C in order to protect from light.Baclofen Tablets are available either in polypropylene containers with polyethylene caps (with optional polyethylene ullage filler, or in PVDC aluminium foil blisters. Date of first authorisation/renewal of the authorisationStart typing to retrieve search suggestions.
Hence, caution should be exercised during concomitant administration of baclofen and levodopa/carbidopa.During pregnancy, especially in the first 3 months, baclofen should only be employed if its use is of vital necessity. Do not crush, break, or chew it. CYTOTOXIC – DO NOT CRUSH TABLETS (NEWT, Sep 2012) 1. Small doses should therefore be used at the start of the treatment, the dose being titrated gradually against the response, under careful supervision. Examples of these drugs include:If you have an allergic reaction, call your doctor or local poison control center right away. If your kidneys aren’t working well, your doctor may lower your dosage of this drug. Serious side effects and their symptoms can include the following:Baclofen oral tablet can interact with other medications, vitamins, or herbs you may be taking.
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