Do not take 2 doses at the same time or extra doses.
Tell your This is not a list of all drugs or health problems that interact with Dulcolax (bisacodyl suppositories). Sanofi, 410 Thames Valley Park Drive, Reading, Berkshire, RG6 1PT, UKTo bookmark a medicine you must sign up and log in.To view the changes to a medicine you must sign up and log in. Patients may experience haematochezia (blood in stool) that is generally mild and self-limiting.If the symptoms worsen during the use of the medicinal product, a doctor or Dizziness and / or syncope have been reported in patients who have taken Dulcolax. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, Renal tubular damage, metabolic alkalosis and muscle weakness secondary to hypokalaemia have also been described in association with chronic laxative abuse.After ingestion of oral forms of Dulcolax, absorption can be minimised or prevented by inducing vomiting or gastric lavage.
After oral and rectal administration, only small amounts of the drug are absorbed and are almost completely conjugated in the intestinal wall and the liver to form the inactive BHPM glucuronide. Electrolyte imbalance may lead to increased sensitivity to cardiac glycosides.The concomitant use of other laxatives may enhance the gastrointestinal side effects of Dulcolax. The details available for these cases suggest that the events would be consistent with defaecation syncope (or syncope attributable to straining at stool), or with a vasovagal response to abdominal pain related to the constipation, and not necessarily to the administration of bisacodyl itself.
Instead, BHPM acts locally in the lower part of the intestine and there is no relationship between the laxative effect and plasma levels of the active moiety. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Adverse events have been ranked under headings of frequency using the following convention: Very common (≥ 1/10); common (≥ 1/100, < 1/10); uncommon (≥ 1/1000, <1/100); rare (≥ 1/10000, <1/1000); very rare (<1/10000). If patients experience abdominal spasm they should avoid potentially hazardous tasks such as driving or operating machinery.The most commonly reported adverse reactions during treatment are abdominal pain and diarrhoea. Following the administration of bisacodyl coated tablets, an average of 51.8% of the dose was recovered in the faeces as free BHPM and an average of 10.5% of the dose was recovered in the urine as BHPM glucuronide. This results in a main release of the drug in the colon, which is the desired site of action.
Stool contained large amounts of BHPM (90% of the total excretion) in addition to small amounts of unchanged bisacodyl.There are no pre-clinical data of relevance to the prescriber which are additional to that already included in other sections of the SPC.In order to protect from light, keep the blister in the outer carton. https://www.webmd.com/drugs/2/drug-3721/dulcolax-bisacodyl-oral Clinical data show that neither the active moiety of bisacodyl (BHPM or bis-(p- hydroxyphenyl)-pyridyl-2-methane) nor its glucuronides are excreted into the milk of healthy lactating females. Stimulation of the rectum causes increased motility and a feeling of rectal fullness.
Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. Bisacodyl should not be used in children aged 4 years or younger.For preparation of diagnostic procedures, in pre- and postoperative treatment when defaecation needs to be facilitated, Dulcolax should be used under medical supervision. doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: If high doses are taken watery stools (diarrhoea), abdominal cramps and a clinically significant loss of fluid, potassium and other electrolytes can occur. If you take Dulcolax (bisacodyl suppositories) on a regular basis, take a missed dose as soon as you think about it. However, many people have no side effects or only have minor side effects. The coated tablets should not be taken together with products which reduce the acidity of the upper gastrointestinal tract, such as milk, antacids or proton pump inhibitors, in order not to prematurely dissolve the enteric coating. All drugs may cause side effects. This site uses cookies.
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Following the administration as a suppository, an average of 3.1% of the dose was recovered as BHPM glucuronide in the urine.
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