Pregnancy and delivery may be prolonged in women treated with erythromycin, ampicillin and clindamycin (Cleocin).Although the diagnosis and treatment of preterm labor are fraught with controversy, there are areas of consensus.
Roberts WE, Edgar BW, Uterine quiescence at 48 hours (primary outcome); delivery at 48 hours, 34 and 37 weeks; and recurrent preterm labor were similar.
In the United States, preterm delivery affects approximately one in 10 births and is the cause of at least 75 percent of neonatal deaths, excluding those related to congenital malformations.Preterm labor is defined as labor that occurs before completion of the 37th week of gestation. International Journal of Reproductive BioMedicine Managing threatened preterm labor was given every 20min. Sherer DM. Hauth JC, Research into biochemical markers such as fetal fibronectin, possible infectious etiologies such as bacterial vaginosis, and the use of more selective tocolytic therapy offers hope that new therapeutic approaches may increase rates of fetal survival.Unfortunately, the incidence of premature birth has not decreased during the past 40 years. Thung SN,
Papiernik E. Preterm labor. Adjunctive erythromycin treatment for idiopathic preterm labor: results of a randomized, double blind, placebo-controlled trial. Nifedipine in the management of preterm labor: a systematic review and metaanalysis. Corliss DK, Name must be less than 100 characters Goldenberg RL,
2015 Jan;53(1):84-91. doi: 10.5414/CP202215.Papatsonis DN, Bos JM, van Geijn HP, Lok CA, Dekker GA.Am J Ther. Beall MH,
-Maintenance dose: 10 to 30 mg orally 3 to 4 times a day. Elsevier Science Graves WL. Preterm labor remains a difficult issue in current obstetrics. et al. Although the cause of preterm labor is unknown, family physicians who provide obstetric care should familiarize themselves and their patients with the predisposing risk factors. Each year members of a different family practice department develop articles for “Problem-Oriented Diagnosis.” This series is coordinated by the Department of Family and Community Medicine at the University of Alabama at Birmingham. eCollection 2014. Maintenance dose Contractions should cease after the initial dose of 20-40 mg PO. This approach is based on the rationale that treatment will prevent perinatal transmission, although this approach is not substantiated in the prevention of preterm labor. Andrews JB, Technical bulletin no. Technical bulletin no.
All women, especially those under 18 or over 40 years of age, should be offered education and/or intervention for family planning, smoking, substance abuse, poor nutrition, sexually transmitted diseases and adverse work conditions that could harm a fetus. Iams JD,
The Alabama preterm birth prevention project. Home uterine activity monitoring. Keyes WG, The necessity for repeat administration of DDAVP or use of any blood products for hemostasis should be determined by laboratory response as well as the clinical condition of the patient. 2011;36(9):HS-13-HS-16.
Elsevier Science Epub 2015 Feb 26.Flenady V, Wojcieszek AM, Papatsonis DN, Stock OM, Murray L, Jardine LA, Carbonne B.Cochrane Database Syst Rev. If contractions continue after 20 minutes, give 10 mg PO q 20 mins for a maximum of 2 doses. Grant A, Hastings C, Dubard MB, Paraskos J, Makowski EL. Kishel MT,
Prevention of preterm birth.
Casal D, Hanaoka S, Patients with intact amniotic membranes and a history of positive group B streptococcal culture are usually treated with intravenous penicillin. Cliver SP, A wet preparation and a potassium hydroxide (KOH) preparation should be obtained, as bacterial vaginosis is strongly associated with preterm labor.After the pelvic examination is completed, the patient should be placed in the lateral recumbent position and externally monitored for fetal heart tones and contractions. Peaceman AM, Whitworth NS, Lis EV,
Carpenter AH. Lescale K,
Effect of corticosteroids for fetal maturation on perinatal outcomes Goodwin TM,
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