0000005985 00000 n 0000003541 00000 n 0000005169 00000 n The table contains a list of drugs found in the Guide that Oral Dosage Forms That Should Not Be Crushed 2016 E.E.S. 0000005404 00000 n Therefore, every effort should be made to determine the lowest effective dosage for the individual patient. 0000003138 00000 n

Some oral dosage forms should not be crushed should not be crushed or chewed. Please check with your pharmacist for additional questions. 0000021530 00000 n 0000001652 00000 n 0000005873 00000 n
low pH of the stomach, and/or to protect the stomach from Oral Dosage Forms That Should Not Be Crushed Mistakes can occur when people have trouble swallowing a tablet or capsule and they try to chew, crush, break or mix the tablet or capsule in food or drink. Ambien CR (zolpidem) Tablet Slow-release Amibid DM (combination) Tablet Slow-release ... Indocin SR (indomethacin) Capsule Slow-release (a,b) should not handle crushed or broken tablets (I) ergocalciferol Capsule Liquid filled (d) ergotamine Tablet Sublingual form (g) erythromycin Tablet Enteric‐coated (b) or delayed release . 400 Easprin EC-Naprosyn Ecotrin Adult Low Strength Ecotrin Maximum Strength Ecotrin Regular Strength Effer-K Effervescent Potassium Effexor XR Embeda E-Mycin Enablex Entocort EC Envarsus XR Epanova 0000008751 00000 n 0000002426 00000 n These formulations can include multiple-layer compressed tablets where drug is released as each layer dissolves, mixed-release pellets that dissolve at different time intervals, and special tablets that are themselves inert but are designed to release drug slowly from the formulation. Some mixed-release capsule formulations can be opened and the contents sprinkled on food. 0000001854 00000 n 0000004119 00000 n 0000028035 00000 n 0000007569 00000 n trailer Some oral dosage forms should not be crushed or chewed. 0000004946 00000 n %PDF-1.6 %âãÏÓ Oral Administration. Some extended-release dosage forms are scored and may be broken in half without affecting the release mechanism but still should not be crushed or chewed.

Tivorbex: Food causes a significant decrease in the rate but not the overall extent of systemic absorption and 1.33 hr delayed Tmax (1.67 hr during fasted vs 3 hr during fed) IV Incompatibilities Some extended-release formulations can be identified by common abbreviations used in their brand names. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. for many of these drugs. These dosage forms have been specially designed to release the drug slowly over several hours, to protect the drug from the low pH of the stomach, and/or to protect the stomach from the irritating effects of the drug. may be different from the slow-release product. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. 151 41 0000025526 00000 n 0000005644 00000 n Oral Dosage Forms That Should Not Be Crushed Mistakes can occur when people have trouble swallowing a tablet or capsule and they try to chew, crush, break or mix the tablet or capsule in food or drink.

These dosage forms have been specially designed to release the drug slowly over several hours, to protect the drug from the low pH of the stomach, and/or to protect the stomach from the irritating effects of the drug. 0000004688 00000 n Oral Dosage Forms That Should Not Be Crushed 2016 . 0000000016 00000 n may stain teeth or mucosal tissue. 0000009647 00000 n oral mucosa irritants, are extremely bitter, or contain dyes that


the irritating effects of the drug. pharmacist for liquid availability and dosing conversions. However, the dose or frequency of administration may be different from the slow-release product. 0000012318 00000 n Check with your pharmacist for liquid availability and dosing conversions.

0000004610 00000 n

< Extended-release (slow release, SR) formulations are designed to release the drug over an extended period of time. Data sources include IBM Watson Micromedex (updated 2 Sep 2020), Cerner Multum™ (updated 1 Sep 2020), … Note: This listing is not comprehensive. However, the dose or frequency of administration 0000032090 00000 n These abbreviations include: CR (controlled release), CRT (controlled-release tablet), LA (long acting), SR (sustained release), TR (time release), SA (sustained action), and XL or XR (extended release). esomeprazole (NexIUM) Capsule Slow‐release (a) etravirine Tablet Note: tablet should be swallowed whole and not crushed; tablet may be dispersed in water Occasionally, drugs should not be crushed because they are

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