(Drugs or herbal products that induce certain enzymes including CYP3A4, may decrease the effectiveness of COCs or increase breakthrough bleeding. Ortho Tri-Cyclen Lo is available in Ortho Tri-Cyclen Lo may interact with phenylbutazone, St. John's wort, antibiotics, Copyright © 2020 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Discontinue Tri-Lo-Sprintec use if pregnancy is confirmed.Administration of COCs to induce withdrawal bleeding should not be used as a test for pregnancy Carefully observe women with a history of depression and discontinue Tri-Lo-Sprintec if depression recurs to a serious degree.The estrogen component of COCs may raise the serum concentrations of thyroxine-binding globulin, sex hormone-binding globulin, and cortisol-binding globulin. Consider discontinuation of Tri-Lo-Sprintec in the case of increased frequency or severity of migraine during COC use (which may be prodromal of a cerebrovascular event).Unscheduled (breakthrough or intracyclic) bleeding and spotting sometimes occur in patients on COCs, especially during the first three months of use. We anticipate reposting the images once we are able identify and filter out images that do not match the information provided in the drug labels. Although NGMN and its metabolites inhibit a variety of P450 enzymes in human liver microsomes, under the recommended dosing regimen, the Following 3 cycles of administration of Tri-Lo-Sprintec, the mean (± SD) elimination half-life values, at steady-state, for NGMN, NG and EE were 28.1 (± 10.6) hours, 36.4 (± 10.2) hours and 17.7 (± 4.4) hours, respectively (Table 2). Women with a history of pregnancy-related cholestasis may be at an increased risk for COC related cholestasis.Carefully monitor prediabetic and diabetic women who take Tri-Lo-Sprintec. The incidence of hypertension increases with increasing concentrations of progestin.Studies suggest a small increased relative risk of developing gallbladder disease among COC users. Due to inconsistencies between the drug labels on DailyMed and the pill images provided by

Yeah the hormone levels are lower in Tri-Sprintec-lo than Sprintec and there are three different levels of them to mimic a natural cycle. However, if you have breast cancer now, or have had it in the past, do not use birth control pills because some breast cancers are sensitive to hormones.Women who use birth control pills may have a slightly higher chance of getting cervical cancer. Tri-Lo-Sprintec is a birth control pill (oral contraceptive) used by women to prevent pregnancy.Your chance of getting pregnant depends on how well you follow the directions for taking your birth control pills. The percent of women who experienced unscheduled bleeding tended to decrease over time.Women who use Tri-Lo-Sprintec may experience amenorrhea. Irregular vaginal bleeding or spotting may happen while you are taking Tri-Lo-Sprintec, especially during the first few months of use.

Table 1: Instructions for Administration of Tri-SprintecStarting COCs in women not currently using hormonal contraception (Day 1 Start or Sunday Start)Due to the potential risk of becoming pregnant, use additional non-hormonal contraception (such as condoms and spermicide) for the first seven days of the patient’s first cycle pack of Tri-Sprintec.Switching to Tri-Sprintec from another oral contraceptiveSwitching from another contraceptive method to Tri-SprintecComplete instructions to facilitate patient counseling on proper tablet usage are located in the FDA-Approved Patient Labeling.Starting Tri-Sprintec after Abortion or MiscarriageThree Ways to Remember in What Order to Take the PillsTable 2: Instructions for Missed Tri-Sprintec TabletsAdditional non-hormonal contraception (such as condoms and spermicide) should be used as back-up if the patient has sex within 7 days after missing tablets.Additional non-hormonal contraception (such as condoms and spermicide) should be used as back-up if the patient has sex within 7 days after missing tablets.We comply with the HONcode standard for trustworthy health information -

Use of this product before menarche is not indicated.Tri-Lo-Sprintec has not been studied in postmenopausal women and is not indicated in this population.The pharmacokinetics of Tri-Lo-Sprintec has not been studied in subjects with hepatic impairment. See full prescribing information for TRI-LO-SPRINTEC. Sprintec is the same dose in every pill, tri-lo sprintec are 3 different doses.

There were no exclusions on the basis of weight; the weight range for women treated was 90 to 240 lbs, with a mean weight of about 142 lbs. Subjects were followed for up to 13 28-day cycles.The following additional adverse drug reactions have been reported from worldwide postmarketing experience with norgestimate/ethinyl estradiol. COCs can reduce milk production in breastfeeding mothers. If the patient has adhered to the prescribed regimen and misses two consecutive periods, rule out pregnancy.Extensive epidemiological studies have revealed no increased risk of birth defects in women who have used oral contraceptives prior to pregnancy. The pharmacokinetics of NGMN is dose proportional following NGM doses of 0.180 to 0.250 mg. Steady-state conditions for NGMN following each NGM dose and for EE were achieved during the three cycle study.

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