The presence of di-carboxylic glutamyl (gla) residues confers calcium-binding properties to these proteins.MGP is found in many connective tissues and is highly expressed in cartilage. And yet, it is rather rare.
It appears that the physiological role of MGP is to act as an inhibitor of mineral deposition. 18 While intriguing, we did not know if this would work in people. Blood samples for biochemical determinations and vascular calcification will be assessed before and after 6 months of Milder forms of vitamin D deficiency are much harder to detect without a blood test, but can and do lead to a huge spectrum of disorders and health problems.
Milder forms of vitamin D deficiency are much harder to detect without a blood test, but can and do lead to a huge spectrum of disorders and health problems. Arterial Calcification and Vitamin K2 Conflicting calcium information Unfortunately, there has been a recent misunderstanding because of a study that showed that those supplementing with 1000 mg/day of calcium had an increase in cardiovascular deaths. These benefits have, so far, not been proven with vitamin K2 supplements, although one study showed some improvements in arterial stiffness. The first is the one generally found in animal fats that haven’t been fermented, while the second is the product of bacterial fermentation. Unfortunately, there has been a recent misunderstanding because of a study that showed that those supplementing with 1000 mg/day of calcium had an increase in cardiovascular deaths.That in conjunction with doctors now testing for arterial calcification, has led to some confusion that calcium supplementation is bad for you.Further, these startling studies did not take into account vitamin K2’s relationship with calcium, and how adequate intakes ensure that calcium is directed to where it needs to be (the bones), and inhibits it from being deposited in the arteries and blood vessels, where it can lead to increased cardiovascular risks.However, vitamin K deficiency results in inadequate activation of MGP, which greatly impairs the calcium removal process and increases the risk of blood vessel calcification.Vitamin K2 is essential for bone and cardiovascular health: without vitamin K2, calcium is not properly directed to bones, allowing it to build up in blood vessel walls and soft tissuesThe population-based Rotterdam study evaluated 4807 healthy men and women aged 55 and older, and the relationship between dietary intake of vitamin K and aortic calcification, heart disease and all-cause mortality.These findings were supported by another population-based study with 16,000 healthy women (aged 49–70) from the Prospect-EPIC cohort population.This 3 year study on postmenopausal women, found that taking 180mcg of MK-7 version of Vitamin K2 daily reduced stiffness in the arteries and improved elasticity in the blood vessels.Lead researcher Cees Vermeer and his colleagues studied 244 postmenopausal women.
The resulting menaquinone is then stored in the fat cells of the animal as well as in the fat of their milk if they are milk-producing. Introduction: Observational studies have shown that high dietary intake of vitamin K2 is associated with reduced risk of coronary vascular disease and vascular calcification. Over the years we received many calls asking if higher dose vitamin K2 could reverse vascular calcification. Interestingly, vitamin K2 concentration in the tissues of both groups were similar, which showed the vitamin K1 was converted into vitamin K2. In human bone, it is concentrated in osteocytes, and its release may be a signal in the bone-turnover cascade (Kasai et al., 1994). (You can read that for yourself I have very good experiences from following Guillaume’s advices on K2 supplementing.It is crucial for everyone to take it as it is almost impossible to get it throughout the year, and as the article states, the body can not storage it.Is MK-7 safe to take with Hashimoto’s? They used ultrasound technology to evaluate thickness and stiffness. Cardiovascular disease—which leads to heart attacks and strokes, and accounts for nearly Arthritis, of which basically everyone past the age of 40 suffers, and increasingly more with time and with age, is a disease of soft tissue calcification. And how many young men and women in their 20s and 30s already have kidney stones and kidney dysfunction? Even more important is inclusion of the MK-4 and MK-7 forms of vitamin K2.The virtue of this formula is that it provides the Other ingredients: extra virgin olive oil, gelatin, glycerin, beeswax, purified water, carob color.Take one softgel daily with a meal, or as recommended by a healthcare practitioner.7. That in conjunction with doctors now testing for arterial calcification, has led to some confusion that calcium supplementation is bad … And this might be enough for you.If it is, you can head to your browser to find and order some K2 supplements (I currently get mine, it’s a 500 mcg per tablet, from Phoenix Nutrition).
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