Thiessen BQ, Wallace SM, Blackburn JL, et al "Increased prescribing of antidepressants subsequent to beta-blocker therapy." Crosson JE, Dunnigan A "Propranolol induced electrical and mechanical alternans in orthodromic reciprocating tachycardia." Imai Y, Watanabe N, Hashimoto J, Nishiyama A, Sakuma H, Sekino H, Omata K, Abe K "Muscle cramps and elevated serum creatine phosphokinase levels induced by beta-adrenoceptor blockers."
Pollack MH, Rosenbaum JF, Cassem NH "Propranolol and depression revisited: three cases and a review." "Product Information. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.
Available for Android and iOS devices. Dornhorst A, Powell SH, Pensky J "Aggravation by propranolol of hyperglycaemic effect of hydrochlorothiazide in type II diabetics without alteration of insulin secretion." It may be necessary to lower the dose of InnoPran XL or to discontinue it.Chronically administered beta-blocking therapy, including InnoPran XL, should not be routinely withdrawn prior to major surgery; however, the impaired ability of the heart to respond to reflex adrenergic stimuli may augment the risks of general anesthesia and surgical procedures.Beta-blockers, like InnoPran XL, may mask tachycardia occurring with hypoglycemia, but other manifestations such as dizziness and sweating may not be significantly affected.InnoPran XL may mask clinical signs of hyperthyroidism, such as tachycardia. The largest and most consistent cardiovascular outcome benefit has been a reduction in the risk of stroke, but reductions in myocardial infarction and cardiovascular mortality also have been seen regularly.Elevated systolic or diastolic pressure causes increased cardiovascular risk, and the absolute risk increase per mm Hg is greater at higher blood pressures, so that even modest reductions of severe hypertension can provide substantial benefit. Aust N Z J Med 8 (1978): 1-632. Postgrad Med J 50 (1974): 253-916. If severe bradycardia develops, reduce or stop InnoPran XL.Beta adrenergic blocker-treated patients treated with epinephrine for a severe anaphylactic reaction may be less responsive to the typical doses of epinephrine. Based on differing results from Ames tests performed by different laboratories, there is equivocal evidence for a genotoxic effect of propranolol HCl in bacteria (In a double-blind, parallel dose-response study in patients with mild-to-moderate hypertension (n=434), doses of InnoPran XL from 80 to 640 mg were taken once daily at approximately 10 p.m. InnoPran XL significantly lowered sitting systolic and diastolic blood pressure when measurements were taken approximately 16 hours later.
Am Heart J 110 (1985): 913-228.
The antihypertensive effects of InnoPran XL were seen in the elderly (≥65 years old) and men and women. Am J Cardiol 72 (1993): 1188-9521. Of the 2 enantiomers of propranolol, the S-enantiomer blocks beta-adrenergic receptors. Postgrad Med J 63 (1987): 57-842. Love JN, Handler JA "Toxic psychosis: an unusual presentation of propranolol intoxication." The signs and symptoms of depression resolved upon substitution with a thiazide diuretic. Generic Name: propranolol Pill with imprint InnoPran XL 80 is Gray & White, Capsule-shape and has been identified as InnoPran XL 80 mg. Am J Cardiol 18 (1966): 361-511. Am Heart J 128 (1994): 1177-8334.
Its structural formula is:Propranolol hydrochloride is a stable, white, crystalline solid, which is readily soluble in water and ethanol. Doses above 120 mg have no additional effects on blood pressure InnoPran XL Extended Release Capsules are supplied as capsules containing either 80 mg or 120 mg of propranolol hydrochloride imprinted with “InnoPran XL”. Martinez-Mir I, Navarro-Badenes J, Palop V, Morales-Olivas FJ, Rubio E "Weight gain induced by long-term propranolol treatment." Beilin LJ, Juel-Jensen BE "Alpha and beta adrenergic blockade in hypertension." O 013.
InnoPran XL® is indicated for the treatment of hypertension, to lower blood pressure. Grant RH, Keelan P, Kernohan RJ, et al "Multicenter trial of propranolol in angina pectoris."
Available for Android and iOS devices. They are available as follows:80 mg: A gray/white capsule, imprinted with ‘InnoPran XL’, ‘80’, and 2 segmented bands, is available in bottles of 30 capsules (NDC 62559-590-30) and professional samples of 7 capsules (NDC 62559-590-77).120 mg: A gray/off-white capsule, imprinted with ‘InnoPran XL’, ‘120’, and 3 segmented bands, is available in bottles of 30 capsules (NDC 62559-591-30) and professional samples of 7 capsules (NDC 62559-591-77).For further product information, please visit www.anipharmaceuticals.com or call 1-800-308-6755.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. It specifically competes with beta-adrenergic receptor-stimulating agents for available receptor sites.
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