The actual price you pay for either drug will depend on your insurance plan.Mavyret is another medication that’s used to treat hepatitis C. Here we look at how Epclusa and Mavyret are alike and different.Epclusa contains two drugs in one pill: velpatasvir and sofosbuvir. For instance, it may cause you to forget to take your medication on time.
Taking two doses at once can increase your risk of side effects.Taking your Epclusa tablets exactly as your doctor prescribes is extremely important. Taking them 12 hours apart also allows each drug to be absorbed by your body without interacting with the other drug.Examples of H2 blockers include famotidine (Pepcid) and cimetidine (Tagamet HB).Taking Epclusa with proton pump inhibitors (PPI) can decrease the amount of Epclusa in your body.
This could make Epclusa less effective. Mavyret also contains two drugs in one pill: glecaprevir and pibrentasvir.Epclusa and Mavyret are both FDA-approved to treat hepatitis C virus (HCV). Mavyret, on the other hand, is only approved as a second treatment for people who have tried certain medications in the past. Epclusa pills should be stored at temperatures up to 86°F (30°C) and kept in the original container.If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it.The following information is provided for clinicians and other healthcare professionals.Epclusa contains two drugs: velpatasvir and sofosbuvir.Velpatasvir inhibits HCV NS5A protein, which is hypothesized to be necessary for efficient phosphorylation of viral RNA. Taking them at the same time allows both drugs to dissolve and be absorbed before the acid-reducing effects of the H2 blocker kicks in. However, it’s more likely that these side effects would be caused by your recovery from the hepatitis C virus.If you have flu-like symptoms after you finish your Epclusa treatment, talk to your doctor.Epclusa will start working right away, but it will take several weeks to a few months to achieve a sustained virologic response (SVR). It comes as a tablet you take by mouth once daily for 12 weeks.Epclusa was approved in 2016 and was the first medication to treat all six hepatitis C genotypes. Your doctor can tell you if your past treatments make you eligible to take Mavyret.Mavyret is also approved for use by people who have received liver or kidney transplants. If the test results show that you have hepatitis B, you may need to take medication to treat it in order to prevent serious liver damage.Epclusa and Harvoni have been compared in clinical studies. Epclusa can be safely used to treat hepatitis C in people who are also infected with HIV.Before taking Epclusa, be sure to tell your doctor about your health history. However, a generic form of Epclusa is due to be released in January 2019.Epclusa can cause mild or serious side effects. It can be used for people with or without cirrhosis (scarring of the liver). However, Epclusa can also be used to treat people with decompensated cirrhosis, while Mavyret cannot.Both medications can be used for people who are treating hepatitis C for the first time. Get medical help right away if you take amiodarone with EPCLUSA and get any of the following symptoms: fainting or near-fainting, dizziness or lightheadedness, not feeling well, weakness, extreme tiredness, shortness of breath, chest pains, confusion, or memory problems. To avoid this interaction, it’s recommended to avoid taking Epclusa with the following antibiotics:There are no reported interactions between Epclusa and ibuprofen.However, Epclusa shouldn’t be taken by people who have severe kidney disease. It will also depend on whether or not you have received treatment for hepatitis C in the past.Examples of other drugs that may be used to treat hepatitis C include:Interferons are medications that were commonly used to treat hepatitis C in the past.
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