Select one or more newsletters to continue. Sumatriptan Tablets can still be used for your next attack.If you take more Sumatriptan Tablets than you shouldDo not take more than six 50 mg tablets or three 100 mg tablets (that’s 300 mg in total) in 24 hours.Taking too much Sumatriptan Tablets could make you ill. The use of hydrochlorothiazide for other indications (e.g., heart disease) in pregnancy should be avoided.There is no information regarding the presence of Micardis HCT or telmisartan in human milk, the effects on the breastfed infant or the effects on milk production. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including the classes to which this drug principally belongs. Relative risk reduction from blood pressure reduction is similar across populations with varying absolute risk, so the absolute benefit is greater in patients who are at higher risk independent of their hypertension (for example, patients with diabetes or hyperlipidemia), and such patients would be expected to benefit from more aggressive treatment to a lower blood pressure goal.Some antihypertensive drugs have smaller blood pressure effects (as monotherapy) in black patients, and many antihypertensive drugs have additional approved indications and effects (e.g., on angina, heart failure, or diabetic kidney disease). Many patients will require more than one drug to achieve blood pressure goals. Therefore, when Micardis HCT and non-steroidal anti-inflammatory agents including selective COX-2 inhibitors are used concomitantly, observe closely to determine if the desired effect of the diuretic is obtained.Dual blockade of the renin-angiotensin-aldosterone system (RAS) with angiotensin blockers, ACE inhibitors, or aliskiren is associated with increased risks of hypotension, hyperkalemia, and renal impairment.

You must tell your doctor if you are taking:ergotamine also used to treat migraine, or similar medicines such as methysergide (see section 2′ Do not use Sumatriptan Tablets’). Tell your doctor if you have any side effect that bothers you or that does not go away. The primary treatment is to discontinue hydrochlorothiazide as rapidly as possible. If you would like more information, talk with your doctor. These medications reduce blood pressure by blocking the actions of a chemical (angiotensin II) that causes blood vessels to constrict or tighten. 3. Stagger the dosage of hydrochlorothiazide and the resin such that hydrochlorothiazide is administered at least 4 hours before or 4 to 6 hours after the administration of the resin.Micardis HCT can cause fetal harm when administered to a pregnant woman. Discuss treatment options with women planning to become pregnant. After a single dose, the glucuronide represents approximately 11% of the measured radioactivity in plasma. It is … See section 4.Each Sumatriptan Tablet contains a single dose of sumatriptan, which belongs to a group of medicines called triptans (also known as 5-HT1 receptor agonists).Sumatriptan Tablets are used to treat migraine headache.Migraine symptoms may be caused by the temporary widening of blood vessels in the head. These assays included bacterial mutagenicity tests with No drug-related effects on the reproductive performance of male and female rats were noted at 100 mg/kg/day (the highest dose administered), about 13 times, on a mg/mTwo-year feeding studies in mice and rats conducted under the auspices of the National Toxicology Program (NTP) uncovered no evidence of a carcinogenic potential of hydrochlorothiazide in female mice (at doses of up to approximately 600 mg/kg/day) or in male and female rats (at doses of up to approximately 100 mg/kg/day). No dose adjustment is required in patients with mild (CrCl 60 to 90 mL/min) or moderate (CrCl 30 to 60 mL/min) renal impairment.Limited data are available with regard to overdosage of telmisartan in humans.

Although the two higher dose combinations appeared to be more toxic (significant decrease in body weight gain) to the dams than either drug alone, there did not appear to be an increase in toxicity to the developing embryos.No teratogenic effects were observed when telmisartan was administered to pregnant rats at oral doses of up to 50 mg/kg/day and to pregnant rabbits at oral doses of up to 45 mg/kg/day. The following side effects have been reported by at least 1% of people taking this medication. Patients who received the combination of ARB and ACE inhibitor did not obtain any additional benefit (no additional reduction of risk of cardiovascular death, myocardial infarction, stroke, or hospitalization from heart failure) compared to ARB monotherapy or ACE inhibitor monotherapy, but experienced an increased incidence of renal dysfunction (e.g., acute renal failure) compared with monotherapy groups.In general, avoid combined use of RAS inhibitors.

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