2020 Mar;8(3):157-168. doi: 10.1016/j.jchf.2019.09.012. Epub 2019 Dec 6. Interaction and transport of thiazide diuretics, loop diuretics, and acetazolamide via rat renal organic anion transporter rOAT1. 2020 Jun;20(3):482-493. doi: 10.1038/s41397-019-0132-y.
2018 Jun;4(1):13-27. doi: 10.1007/s41030-018-0052-z. Concurrent use of chlorpromazine with methoxsalen, trixsalen, or tetracycline can potentiate intraocular photochemical damage. Lasix is a type of “loop” diuretic while thiazides refer to a class of diuretics. Clipboard, Search History, and several other advanced features are temporarily unavailable.

Lasix is a brand name for furosemide. Uwai Y, et al. Plasma levels do not correlate with diuretic effects. Epub 2011 Feb 18.G Ital Cardiol (Rome). Elsevier Science The onset of diuretic action occurs at 2 h with the exception of metolazone whose onset is 1 h, indapamide 1–2 h, and chlorthalidone 2–3 h. Peak diuretic effects occur within 2 h for indapamide and metolazone, 2–6 h for chlorthalidone, 4–6 h for benzthiazide and hydrochlorothiazide, 4 h for bendroflumethiazide, chlorothiazide, and hydroflumethiazide, and 6 h for methyclothiazide, polythiazide, quienthazone, and trichlormethiazide. Volume overload is an important clinical target in heart failure management, typically addressed using loop diuretics. The antihypertensive effects of these agents may not appear for 3–4 days with maximum effect being delayed for 3–4 weeks. Epub 2018 Apr 5.Carpenter RJ, Kouyoumjian S, Moromisato DY, Lieu P, Amirnovin R.J Pediatr Pharmacol Ther. Thiazide diuretics are used in the management of edema, the management of hypertension, the treatment of nephrogenic diabetes insipidus, and the prophylaxis of renal calculus formation.Thiazide diuretics at their prescribed dosages are safe to use.
Concurrent use of chlorpromazine with medications known to alter hepatic microsomal enzyme activity may result in increased hepatotoxicity. Chlorpromazine should not be taken or administered in combination with any other prescription or over-the-counter medications or herbal agents without approval from the physician.We use cookies to help provide and enhance our service and tailor content and ads. Uwai Y, Saito H, Hashimoto Y, Inui KI. Chlorpromazine has potentiated the effects of the following classes of compounds: oral hypoglycemic agents, beta blockers, dopamine, appetite suppressants, antiemetics, barbiturates, thiazide diuretics, lithium, hypotensives, tricyclic antidepressants, anticholinergics, antithyroid medication, monoamine oxidase inhibitors, ophthalmics, anticonvulsants, antidyskinetics, antihistamines, cold remedies, and opioid analgesics. Although potentially able to induce diuresis in patients otherwise resistant to high doses of loop diuretics, this strategy has not been subjected to large-scale clinical trials to establish safety and clinical efficacy. Serum and urine electrolyte levels should be monitored. Synonyms of this drug are clotride, diupres, diuril, and others.Chlorpromazine may inhibit or enhance the effects of other agents or medications. Concurrent use of metrizamide can lower the seizure threshold. rize the existing literature evaluating the combination of loop and thiazide diuretics in patients with heart failure in order to describe the possible benefits and hazards associated with this therapy.

As diuretics they are usually used in combination with a loop diuretic to augment the diuresis in patients with refractory edema. No specific antidotes are available for thiazide diuretics. J Pharmacol Exp Ther.

Unable to load your collection due to an error 2010 Aug;11(8):571-4. doi: 10.2459/JCM.0b013e32833d37b9.Herz. Lasix and thiazides are different types of diuretics. It is especially recommended for hypertonic illnesses.

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