Ezetimibe is classified by the FDA as a pregnancy risk category C drug. Ezetimibe is a white, crystalline powder that is freely to very soluble in ethanol, methanol, and acetone and practically insoluble in water. PK ! Pregnancy: Pregnancy Category C Labor and Delivery: None Nursing Mothers: It is not known whether ezetimibe is excreted into human breast milk.If used, the potential benefit should justify the potential risk to the infant. This drug decreases cholesterol synthesis and possibly the synthesis of other biologically active substance derived from cholesterol. Ezetimibe is classified by the FDA as a pregnancy risk category C drug. Ezetimibe is used alone or in combination with other cholesterol-lowering drugs. Benefit should outweigh risk US FDA pregnancy category: Not assigned Risk Summary: There are no data available on bempedoic acid in human pregnancy to inform a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes; there is insufficient data with ezetimibe. Liptruzet is ezetimibe and atorvastatin; ... (above) to see a review of ezetimibe with simvastatin in the Taylor & Francis journal Expert Opinion on Drug Safety. Pregnancy Category C: There are no adequate and well-controlled studies of ezetimibe in pregnant women. [See CONTRAINDICATIONS] Nursing Mothers. Ezetimibe should be used during pregnancy only if … PREGNANCY CATEGORY: C Pregnancy category is X when combined with a statin.

Ezetimibe should be used during pregnancy only if the potential benefit justifies the risk to the fetus. Ezetimibe; Simvastatin should only be administered to females of child-bearing potential, including adolescents at least 1-year post-menarche, when such patients are highly unlikely to conceive and have been informed of the potential hazards. Liptruzet is ezetimibe and atorvastatin; vytorin is ezetimibe and simvastatin.In order to deliver a personalised, responsive service and to improve the site, we remember and store information about how you use it. [29596] Ezetimibe; simvastatin is contraindicated for use in breast-feeding women. This drug may cause harm to breast fed infant based on its mechanism of action. When ezetimibe is administered with a statin in a woman of childbearing potential, refer to the pregnancy category and product labeling for the statin [see Contraindications (4)]. is defined as drugs which have caused, ... Ezetimibe should be used in pregnancy only if the potential benefit exceeds the potential risk. Ezetrol (Merck); Liptruzet (Merck Sharpe & Dohme); Vytorin (MSD); Zetia (Merck) (Note that non-subscribers to the journal will only be able to see an abstract of the article.) AU TGA pregnancy category: B3 US FDA pregnancy category: C. See references. Ezetimibe is a medication used to treat high blood cholesterol and certain other lipid abnormalities. However, based on this drug's action to decrease cholesterol synthesis and other biologically active substances derived from cholesterol, this drug may cause fetal harm when administered to pregnant women. Ezetimibe - Get up-to-date information on Ezetimibe side effects, uses, dosage, overdose, pregnancy, alcohol and more. We comply with the HONcode standard for trustworthy health information - Description: Ezetimibe localises at the brush border of the small intestine and inhibits absorption of cholesterol via the sterol transporter, Niemann-Pick C1-Like1 (NPC1L1).This results in decreased delivery of cholesterol to the liver, reduction of hepatic cholesterol stores and … This drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. ��`S__�_x �C��CR�ť ... Ezetimibe falls into category C. In animal studies, pregnant animals were given this medication and had some babies born with problems. Hyperlipidemia is generally not a condition necessary to treat during pregnancy. All Rights Reserved. Renal Impairment: When used as mono-therapy, no dosage adjustment is necessary. Available for Android and iOS devices. �C�=���i{5�%��6�o���φ� t�)8�w��s�7[UFO`�4:%WɌD��R�R�s�-�L"�LV )ف#7�����].��ڥ�@��P�x���T��Hn�b�����V@�g�O���1�� ��W�ٺ��n�_7N2�It��/H��UU)9Co�>iq$���k�щ)�>{��v�7*?�K�m�0�]gk�Hw��� �Ld�T�+�ɺBV�B9�Ծ��b+D��w�|�tc��m`�1��Ze ���QeҒ����_;4�*�DP�T�*k��X��f���B�Uֻ�~F��Dm�����@�_����`=i$������{���3�x�����^�~L����Hnj�S|��k���Á�k� &��?N�D��aM�߀�_�� 0P��i�W����?�Mǒe%L�`��]�)��s�N�1�$�U]_��1��0�C��c��o[E���B�(@�V��F�7�qZ�ȋ� �� PK ! Generally it is used together with dietary changes and a statin.

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