104. Andreasen JJ, Orskov C, Holst JJ. The increased gastrointestinal tract symptoms in patients treated with Precose are a manifestation of the mechanism of action of Precose and are related to the presence of undigested carbohydrate in the lower GI tract.If the prescribed diet is not observed, the intestinal side effects may be intensified. Because current information strongly suggests that abnormal blood glucose levels during pregnancy are associated with a higher incidence of congenital anomalies as well as increased neonatal morbidity and mortality, most experts recommend that insulin be used during pregnancy to maintain blood glucose levels as close to normal as possible.A small amount of radioactivity has been found in the milk of lactating rats after administration of radiolabeled acarbose. Virji A, Murr MM. Machella TE. Association with inhibition of gastric acid secretion in humans. van der Kleij FG, Vecht J, Lamers CB, Masclee AA. Available for Android and iOS devices. Factors responsible for the symptoms. At such times, temporary insulin therapy may be necessary.Patients should be told to take Precose orally three times a day at the start (with the first bite) of each main meal. They are most commonly mild-to-moderate gastrointestinal effects, such as flatulence, diarrhea, or abdominal discomfort, and generally diminish in frequency and intensity with time.Therapeutic response to Precose should be monitored by periodic blood glucose tests.
Metabolic effects of acarbose in young healthy men. The effect of short-term alpha-glucosidase inhibition on carbohydrate and lipid metabolism in type II (noninsulin-dependent) diabetics.
Prospective controlled vagotomy trial for duodenal ulcer. Starch-targeting enzymes are typically found within glycoside hydrolase family 13 (GH13) and are one of the most well-represented carbohydrate-active enzyme families found within the genomes of many different gut bacteria (Beyond the treatments of diabetes and prediabetes, acarbose has received recent attention as an agent that may extend life span in mice. Octreotide therapy in dumping syndrome: Analysis of long-term results. 25. Insulin lispro in the treatment of patients with type 2 diabetes mellitus after oral agent failure. OTUs that significantly changed in response to acarbose treatment were identified by repeated measures analysis of variance (ANOVA) on each OTU, with correction for multiple comparisons.
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In the diet, sulfonylurea and metformin groups, the mean decrease in HbA1c produced by the addition of Precose was statistically significant at six months, and this effect was persistent at one year. Octreotide influences small intestinal motility and transit time in fasting and fed states. Carvajal SH, Mulvihill SJ.
Blackburn AM, Christofides ND, Ghatei MA, et al. Diseases & Conditions "Dumping stomach" and other results of gastrojejunostomy: operative cure by disconnecting old stoma. Acarbose use increased in the Asian patients, but no glycaemic interaction with allocated study medication was observed (adjusted P = .12). Effect of starch malabsorption on colonic function and metabolism in humans.
Systematic review: applications and future of gastric electrical stimulation. alinia-nitazoxanide-342664 Sailer D, Röder G. Treatment of non-insulin dependent diabetic adults with a new glycoside hydrolase inhibitor (Bay g 5421).
Efficacy of depot long-acting release octreotide therapy in severe dumping syndrome.
Multicenter, placebo-controlled trial comparing acarbose (BAY g 5421) with placebo, tolbutamide, and tolbutamide-plus-acarbose in non-insulin-dependent diabetes mellitus.
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