No clinical benefit demonstrated in the management of patients with type 2 diabetes Insufficient clinical benefit in the localisation of known lesions of well-differentiated hepatocellular carcinoma and the characterisation of liver nodules and/or staging in the search of lesions of hepatocellular carcinoma
dans la douleur aiguë moyenne à sévère
No clinical benefit demonstrated in the treatment of relapsing forms of multiple sclerosis.
Pas d’avantage clinique démontré dans la prise en charge des troubles de la marche des patients ayant une sclérose en plaques Minor improvement in the treatment of adults with ALK+ advanced non-small cell lung cancer previously treated with crizotinib
No clinical benefit demonstrated by comparison with liposomal daunorubicin, in patients at an advanced stage of the HIV infection with extensive mucocutaneous or visceral Kaposi’s sarcoma who have an incomplete response to antiretroviral treatment.
6-copena; 8y; a Curitybina; AAS INFANTIL IMA; AAS ADULTO IMA; Aas Protect; Aasedantil Insufficient clinical benefit in the absence of any role in the diagnostic strategy for
No clinical benefit demonstrated, in monotherapy or in combination with dexamethasone, in relapsed multiple myeloma in patients who have already undergone or who are ineligible for a haematopoietic stem cell transplant
For the treatment of non-small cell lung cancer with ROS1 rearrangement, low clinical benefit for first-line treatment, moderate benefit for second-line and subsequent treatments, and no proven clinical added value for the management of this cancer High clinical benefit, in combination with rituximab, for the treatment of chronic lymphocytic leukaemia for patients who are not eligible for any other treatment but no proven clinical added value for the therapeutic strategy in respect of these patients Please fill in your email address to retrieve your email alerts subscriptions.
No clinical benefit demonstrated in the management of complicated intra-abdominal, skin and soft tissue infections in children – pas d’avantage clinique démontré en première ligne
Avis défavorable au maintien du remboursement des PCI de haute osmolalité but no proven clinical added value compared to COSENTYX and TALTZ.
Avis défavorable au maintien du remboursement des PCI de haute osmolalité
Bains de bouche à base de :
No clinical benefit demonstrated by comparison with other coagulation factor VIII products in the treatment and prophylaxis of bleeding in patients with haemophilia A. No clinical benefit demonstrated in the treatment of hyperphosphataemia in patients on dialysis for chronic kidney failure compared with sevelamer carbonate No clinical benefit demonstrated in current treatment of severe bleeding in patients with acquired haemophilia No clinical added value demonstrated for vildagliptin combined with metformin and a sulfonylurea by comparison with triple therapy in the management of type 2 diabetes No clinical benefit demonstrated in prevention of nausea and vomiting after highly emetogenic chemotherapy compared with the standard treatment (setron + aprepitant + corticosteroid)
Progrès thérapeutique modéré dans le cancer métastatique de la prostate
Progrès thérapeutique modéré dans la prise en charge de la mucopolysaccharidose de type VI
réduction du LDL-c recherchée. Improvement in treatment by YTTRIGA on its own cannot be assessed.
de CERIS, VESICARE et TOVIAZ par rapport à DITROPAN
Intérêt conservé dans la prise en charge des douleurs chroniques d’origine cancéreuse, intenses ou rebelles aux autres antalgiques, en cas de douleurs stables. Pas d’intérêt clinique démontré dans la prévention de la perte osseuse New presentation in concentrate for solution for infusion in addition to oral forms Bulas de Vários Medicamentos.
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