It also has a mild drying effect, which allows excess oils and dirt to be easily washed away from the skin.
Clindamycin phosphate and benzoyl peroxide gel, 1.2% / 5% should be used with caution in patients receiving such agents.Use of topical benzoyl-peroxide-containing preparations with topical sulfone products may cause skin and facial hair to temporarily change color (yellow/orange).There are no adequate and well-controlled studies in pregnant women treated with clindamycin phosphate and benzoyl peroxide gel, 1.2% / 5%. Severe colitis may result in death.Studies indicate a toxin(s) produced by Clostridia is one primary cause of antibiotic-associated colitis. Patients were instructed to avoid sun exposure. Refer to storage information printed on your package for the exact temperature range. Benzoyl peroxide has been found to cause DNA strand breaks in a variety of mammalian cell types, to be mutagenic in S. typhimurium tests by some but not all investigators, and to cause sister chromatid exchanges in Chinese hamster ovary cells.
Because many drugs are excreted in human milk, caution should be exercised when clindamycin phosphate and benzoyl peroxide gel, 1.2% / 5% is administered to a nursing woman.Safety and effectiveness of clindamycin phosphate and benzoyl peroxide gel, 1.2% / 5% in pediatric patients below the age of 12 have not been established.Clinical studies of clindamycin phosphate and benzoyl peroxide gel, 1.2% / 5% did not include sufficient numbers of subjects ages 65 and over to determine whether they respond differently from younger subjects.Clindamycin Phosphate and Benzoyl Peroxide Gel, 1.2% / 5% is a fixed combination product with two active ingredients in a white to slightly yellow, opaque, aqueous gel formulation. Clindamycin phosphate and benzoyl peroxide gel refrigerator SDS. Avoid the eyes, mouth, lips, mucous membranes, or areas of broken skin.Clindamycin phosphate and benzoyl peroxide gel, 1.2% / 5% is not for oral, ophthalmic, or intravaginal use.Clindamycin phosphate and benzoyl peroxide gel, 1.2% / 5% is a white to slightly yellow, opaque gel. https://www.webmd.com/drugs/2/drug-1344/benzoyl-peroxide-topical Wet the If using the shaving cream, first wet the area to be shaved. Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin.Clindamycin phosphate has molecular weight of 504.97 and its chemical name is Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside 2-(dihydrogen phosphate).Clindamycin and Benzoyl Peroxide Gel, 1%/5% also contains benzoyl peroxide, for topical use.Each gram of Clindamycin and Benzoyl Peroxide Gel, 1%/5% contains, as dispensed, 10 mg (1%) clindamycin as phosphate and 50 mg (5%) benzoyl peroxide in a base of carbomer homopolymer type C, potassium hydroxide, propylene glycol, and purified water.Benzoyl peroxide has been shown to be absorbed by the skin where it is converted to benzoic acid. USE OF THE TOPICAL FORMULATION OF CLINDAMYCIN RESULTS IN ABSORPTION OF THE ANTIBIOTIC FROM THE SKIN SURFACE. Less than 2% of the dose enters systemic circulation as benzoic acid.Clindamycin binds to the 50S ribosomal subunits of susceptible bacteria and prevents elongation of peptide chains by interfering with peptidyl transfer, thereby suppressing protein synthesis.Benzoyl peroxide has been shown to be a tumor promoter and progression agent in a number of animal studies. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Luperox® A98 anhydrous benzoyl peroxide … It is suggested that the lipophilic nature of benzoyl peroxide acts to concentrate the compound into the lipid-rich sebaceous follicle.The pharmacokinetics (plasma and urine) of clindamycin from Clindamycin and Benzoyl Peroxide Gel, 1%/5% was studied in male and female patients (n=13) with acne vulgaris. Percent reductions in inflammatory lesion counts after treatment for 11 weeks in these 5 trials are shown in Table 2.Clindamycin Phosphate and Benzoyl Peroxide Gel, 1.2% / 5%The group treated with clindamycin phosphate and benzoyl peroxide gel, 1.2% / 5% showed greater overall improvement in the investigator’s global assessment than the benzoyl peroxide, clindamycin, and vehicle groups in three of the five trials (Trials 1, 2, and 5).Clinical trials have not adequately demonstrated the effectiveness of clindamycin phosphate and benzoyl peroxide gel, 1.2% / 5% versus benzoyl peroxide alone in the treatment of non-inflammatory lesions of acne.Clindamycin Phosphate and Benzoyl Peroxide Gel, 1.2% / 5% is a white to slightly yellow, opaque gel. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. Put a thin layer of gel on all the affected areas. Updated Benzoyl peroxide topical (for the skin) is used to treat acne.
Erythromycin and benzoyl peroxide may also be used for other purposes not listed here. Manufactured by TOLMAR Inc., Fort Collins, CO 80526 for Copy the URL below and paste it into your RSS Reader application. It may take several weeks to see the full effects.
How to use benzoyl peroxide 5% gel.
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