Terazosin is also used to high blood pressure. And the researchers found that those treated with terazosin seemed to have less severe symptoms and slower progression of their Parkinson’s. The reason for this protection was thought to be because the drug may provide brain cells with more energy by boosting an enzyme called PGK1.In addition to studying the potential of terazosin in the lab, the researchers also looked at existing data from those taking the drug.By comparing data from 150,000 people treated for an enlarged prostate - where half were on drugs such as terazosin and half were on alternative medication that didn’t affect PGK1 - they found that those on terazosin were less likely to develop Parkinson’s.
A drug used to treat enlarged prostates may have exciting potential for slowing down Parkinson's, according to research published in the Journal of Clinical Investigation. Existing data from people with Parkinson’s who have been treated for an enlarged prostate was also used in the study. The older the women were, the bigger the difference in symptoms was between those who had and had not taken estrogen. Also, women with Parkinson's disease tend to have more difficulty with their symptoms a few days before and during their menstrual period, which suggests that the hormone does have a role.There is also good evidence that taking estrogen after menopause helps prevent other Saunders-Pullman expects future research will help clarify the role of estrogen in preventing WebMD does not provide medical advice, diagnosis or treatment. Terazosin is a drug that has already been shown to be safe and approved as a treatment and the results from this study highlight the potential for this drug to be investigated as a repurposed drug for Parkinson’s.

This led to increased dopamine levels and improved movement symptoms. Drug that treats an enlarged prostate may 'slow disability' in Parkinson's sufferers by 'blocking cell death in the brain' Drug terazosin, approved for … Collaborating researchers at the University of Iowa and Capital Medical University in Beijing, China, found that a drug used to treat enlarged prostate, terazosin, appears able to slow the progress of Parkinson’s disease. She presented the current knowledge of estrogen and Parkinson's disease this week at a medical conference held here. "Find out what drug repurposing means and take a look ar some of the drugs in clinical trials for Parkinson's.The Parkinson’s UK helpline is a free and confidential service providing support to anyone affected by Parkinson’s.Parkinson's UK is the operating name of the Parkinson's Disease Society of the United Kingdom. Terazosin, a drug for enlarged prostate, might also be able to slow the progression of Parkinson's disease, tests in animal models and analyses of patient data have shown. The research was published in The Journal of Clinical Investigation. The study suggests that the prostate drug, terazosin, can protect brain cells to slow the progression of Parkinson’s. Repurposing can allow new treatments to become available much more easily, quickly and cheaply. According to the researchers, their findings suggest that estrogen might actually help protect the Saunders-Pullman is an assistant professor of neurology at Albert Einstein College of Medicine and Beth Israel Medical Center in New York City. Aug. 7, 2001 (Quebec City) -- The debate over whether the female hormone Expert Rachel Saunders-Pullman, MD, and her colleagues looked at the health records of 138 women with Parkinson's disease who had passed menopause. However, women who have Parkinson's disease and start or stop taking hormone replacement therapy for other reasons should be aware that doing so could affect their More evidence that estrogen plays a role in Parkinson's disease comes from studies showing that menopausal women with this condition tend to respond better to treatment if they are taking estrogen.
The researchers showed that the prostate drug was able to slow the loss of brain cells in various models of Parkinson’s, including in mice. However, women who had taken hormone replacement therapy had less severe symptoms than those who had never taken estrogen. What the team did The study suggests that the prostate drug, terazosin, can protect brain cells to slow the progression of Parkinson’s. The prostate drug now needs to be tested in clinical trials to see if it alters the progression of Parkinson’s, Professor David Dexter, Deputy Director of Research at Parkinson's UK, says:"These exciting results show that terazosin may have hidden potential for slowing the progression of Parkinson's, something that is desperately needed to help people live well for longer. "While it is early days, both animal models and studies looking at people who already take the drug show promising signs that need to be investigated further. A registered charity in England and Wales (258197) and in Scotland (SC037554). Thirty-four of these women had taken Not surprisingly, the longer the women had been suffering from Parkinson's disease, the worse their symptoms were. More evidence that estrogen plays a role in Parkinson's disease comes from studies showing that menopausal women with this condition tend to respond better to treatment if they are taking estrogen.

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