By continuing to view the drug information, you agree to abide by such terms of use.You are encouraged to report negative side effects of prescription drugs to the FDA. Absorption of intramuscular lorazepam was rapid. Ativan is a brand-name prescription medication that's used to treat anxiety, insomnia (trouble sleeping), and status epilepticus (a severe type of seizure). Do not shake vigorously, as this will result in air entrapment. Available for Android and iOS devices. Lorazepam, a benzodiazepine with antianxiety, sedative, and anticonvulsant effects, is intended for the intramuscular or intravenous routes of administration. In those patients in whom a greater likelihood of lack of recall for perioperative events would be beneficial, larger doses as high as 0.05 mg/kg up to a total of 4 mg may be administered (see There are insufficient data to support efficacy or make dosage recommendations for intravenous lorazepam in patients less than 18 years of age; therefore, such use is not recommended.No dosage adjustments are needed in elderly patients and in patients with hepatic disease.For acute dose administration, adjustment is not needed for patients with renal disease. HOW TO USE: This is a sublingual tablet. The liquid contains 1mg of lorazepam in each 1ml. It is used to treat anxiety disorders, trouble sleeping, active seizures including status epilepticus, alcohol withdrawal, and chemotherapy-induced nausea and vomiting.

I would recommend, for recreational use, 1 mg lorazepam if you have no benzo tolerance. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. A comprehensive review of the considerations critical to the informed and prudent management of status epilepticus cannot be provided in drug product labeling. It has the chemical formula: 7-chloro-5(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1, 4-benzodiazepin-2-one. ATIVAN (lorazepam) Injection. Visit the Selected from data included with permission and copyrighted by First Databank, Inc. Data sources include IBM Watson Micromedex (updated 2 Sep 2020), Cerner Multum™ (updated 1 Sep 2020), … This dose will suffice for sedating most adult patients and ordinarily should not be exceeded in patients over 50 years of age. However, in patients with renal disease, caution should be exercised if frequent doses are given over relatively short periods of time (see also The dose of ATIVAN should be reduced by 50% when coadministered with probenecid or valproate (see It may be necessary to increase the dose of ATIVAN in female patients who are concomitantly taking oral contraceptives.When given intramuscularly, ATIVAN Injection, undiluted, should be injected deep in the muscle mass.Injectable ATIVAN can be used with atropine sulfate, narcotic analgesics, other parenterally used analgesics, commonly used anesthetics, and muscle relaxants.Immediately prior to intravenous use, ATIVAN Injection must be diluted with an equal volume of compatible solution. However, this is still a single-dose model meant to demonstrate the suitability of the sublingual lorazepam formulation in administering lorazepam to clinical effect.

The treatment of status, however, requires far more than the administration of an anticonvulsant agent. Because status epilepticus may result from a correctable acute cause such as hypoglycemia, hyponatremia, or other metabolic or toxic derangement, such an abnormality must be immediately sought and corrected. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of particular drug is safe, appropriate or effective for you or anyone else. For the primary purpose of sedation and relief of anxiety, the usual recommended initial dose of lorazepam for intravenous injection is 2 mg total, or 0.02 mg/lb (0.044 mg/kg), whichever is smaller. This dose will most likely bring about a good deal of anxiolysis (anxiety-relief), a sense of being somewhat "calmer" or "more tranquil", relaxation of the body (in the muscles), possible sleepiness, somewhat impaired and slowed cognition and judgment, somewhat disinhibited behavior, a possible … When properly diluted, the drug may be injected directly into a vein or into the tubing of an existing intravenous infusion. However, when an intravenous port is not available, the IM route may prove useful (see The safety of ATIVAN in pediatric patients has not been established.For the designated indications as a premedicant, the usual recommended dose of lorazepam for intramuscular injection is 0.05 mg/kg up to a maximum of 4 mg. As with all premedicant drugs, the dose should be individualized (see also There are insufficient data to support efficacy or make dosage recommendations for intramuscular lorazepam in patients less than 18 years of age; therefore, such use is not recommended.For the primary purpose of sedation and relief of anxiety, the usual recommended initial dose of lorazepam for intravenous injection is 2 mg total, or 0.02 mg/lb (0.044 mg/kg), whichever is smaller.

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