You may need to use blood pressure medication for the rest of your life.You should not use this medicine if you are allergic to nifedipine, if you have severe coronary artery disease, or if you have had a heart attack within the past 2 weeks.To make sure nifedipine is safe for you, tell your doctor if you have:severe COPD (chronic obstructive pulmonary disease);if you take other medications, especially an antibiotic or antifungal medicine, an antidepressant, heart or blood pressure medicine, or drugs to treat HIV/AIDS or hepatitis C.It is not known whether nifedipine will harm an unborn baby. A patient is admitted to the emergency department with chest pain that is unrelieved with sublingual organic nitrates. You may need to stop using the medicine for a short time.Do not stop taking nifedipine without first talking to your doctor, even if you feel fine. Call your doctor for medical advice about side effects. Excessive lowering of blood pressure (hypotension) during initiation of nifedipine treatment can occur, especially in patients already taking another blood pressure lowering drug.
of moderate to severe hypertension and seems to be an effective nonparenteral agent DESCRIPTION.
in one to five minutes, and the maximal effect in 20 to 38 minutes, with return to It works by relaxing the muscles of your heart and blood vessels.Nifedipine is used to treat hypertension (high blood pressure) and angina (chest pain).Nifedipine may also be used for purposes not listed in this medication guide.You should not use nifedipine if you have severe coronary artery disease, or if you have had a heart attack within the past 2 weeks.Before taking nifedipine, tell your doctor if you have kidney or liver disease, a blockage in your digestive tract (stomach or intestines), a history of stomach surgery, coronary artery disease, underactive thyroid, diabetes, or congestive heart failure.If you need surgery, tell the surgeon ahead of time that you are using nifedipine. All Rights Reserved.to download free article PDFs,
Skip the missed dose if it is almost time for your next scheduled dose. Despite this decision and despite authoritative voicesMesserli FH, Grossman E. The Use of Sublingual NifedipineCustomize your JAMA Network experience by selecting one or more topics from the list below. SUBLINGUAL NIFEDIPINE (20MG) IN PATIENTS WITH SEVERE HYPERTENSION SYSTOLIC Adverse Reactions Both doses of nifedipine were well tolerated. Customize your JAMA Network experience by selecting one or more topics from the list below. High blood pressure often has no symptoms. PROCARDIA® (nifedipine) is an antianginal drug belonging to a class of pharmacological agents, the calcium channel blockers.Nifedipine is 3,5-pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2- nitrophenyl)-, dimethyl ester, C 17 H 18 N 2 O 6, and has the structural formula: Sublingual dosing leads to a C max of 10ng/mL, with a T max of 50min, and an AUC of 25ng\\*h/mL. Version: 12.01.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. In group B, systolic blood pressure decreased from 203.8±22.1 mm
sign up for alerts, and moreto download free article PDFs, Ceyhan B et al., 5 compared the antihypertensive effects of sublingual nifedipine and sublingual captopril in 52 patients with hypertensive emergencies: 25 mg captopril and 10 mg nifedipine were given sublingually to 28 and 24 patients respectively. The effects of sublingual nifedipine were seen Bay-a 1040, a new coronary dilator.Short and long-term efficacy of a calcium-antagonist agent (Nifedipine) combined with methyldopa in the treatment of severe hypertension.© 1981 The American College of Chest Physicians. Nifedipine may also be used for purposes not listed in this medication guide. Published by Elsevier Inc. All rights reserved.
IN 1995, the Cardiorenal Advisory Committee of the Food and Drug Administration, after a lengthy deliberation, unanimously decided that sublingual nifedipine should not officially be approved for the treatment of hypertensive emergencies.
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