The clinical significance of 156 these findings is unknown. 0000007729 00000 n trailer 0000002659 00000 n
Time to maximum plasma concentration (TIn another clinical study in adults, two inhalations of Albuterol sulfate inhalation aerosol taken 30 minutes before exercise prevented exercise-induced bronchospasm as demonstrated by the maintenance of FEVIn a 4-week, randomized, open-label trial, 63 children, 4 to 11 years of age, with asthma were evaluated for the bronchodilator efficacy of Albuterol sulfate inhalation aerosol (33 pediatric patients) in comparison to a CFC 11/12 propelled albuterol inhaler (30 pediatric patients).In another clinical study in pediatric patients, two inhalations of Albuterol sulfate inhalation aerosol taken 30 minutes before exercise provided comparable protection against exercise-induced bronchospasm as a CFC 11/12 propelled albuterol inhaler.Large doses of intravenous albuterol have been reported to aggravate preexisting diabetes mellitus and ketoacidosis. While you are taking Albuterol sulfate inhalation aerosol, other inhaled drugs and asthma medications should be taken only as directed by your physician.Common adverse effects of treatment with inhaled albuterol include palpitations, chest pain, rapid heart rate, tremor, or nervousness. This does not include the sprays of medicine used for priming your inhaler.It is very important that you keep the mouthpiece clean so that medicine will not build up and block the spray through the mouthpiece. 418 32 0000003926 00000 n Albuterol sulfate inhalation aerosol should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.During worldwide marketing experience, various congenital anomalies, including cleft palate and limb defects, have been reported in the offspring of patients being treated with albuterol.
0000000016 00000 n 152 Albuterol Sulfate HFA Inhalation Aerosol at recommended doses, if they occur, 153 the drug may need to be discontinued.
INHALER MAY CEASE TO DELIVER MEDICATION IF NOT PROPERLY CLEANED.The mouthpiece should be cleaned (with the canister removed) by running warm water through the top and bottom for 30 seconds at least once a week. Read and follow these instructions carefully. As with all sympathomimetic medications, cardiac arrest and even death may be associated with abuse of Albuterol sulfate inhalation aerosol. If you are pregnant or nursing, contact your physician about use of Albuterol sulfate inhalation aerosol. The inhalation solution and nebulizer will come with patient instructions. Select one or more newsletters to continue. 0000004170 00000 n The judicious use of a cardioselective beta-receptor blocker may be considered, bearing in mind that such medication can produce bronchospasm. 0000005424 00000 n
Prescribing Information . Albuterol sulfate inhalation aerosol should be discarded when the dose indicator display window shows zero.To maintain proper use of this product, it is important that the mouthpiece be washed and dried thoroughly at least once a week. Available for Android and iOS devices. 0000016728 00000 n
Albuterol sulfate inhalation aerosol is supplied as a pressurized aluminum canister with an attached dose indicator, a white plastic actuator and orange dust cap each in boxes of one. In addition, albuterol, like other sympathomimetic agents, can cause adverse reactions such as hypertension, angina, vertigo, central nervous system stimulation, insomnia, headache, metabolic acidosis, and drying or irritation of the oropharynx.Hypokalemia may also occur. Do not puncture or incinerate. More frequent administration or higher doses are not recommended. Controlled clinical studies and other clinical experience have shown that inhaled albuterol, like other beta-adrenergic agonist drugs, can produce a significant cardiovascular effect in some patients, as measured by pulse rate, blood pressure, symptoms, and/or electrocardiographic changes.Studies in laboratory animals (minipigs, rodents, and dogs) have demonstrated the occurrence of cardiac arrhythmias and sudden death (with histologic evidence of myocardial necrosis) when betaPropellant HFA-134a is devoid of pharmacological activity except at very high doses in animals (380‑1300 times the maximum human exposure based on comparisons of AUC values), primarily producing ataxia, tremors, dyspnea, or salivation. 0000008687 00000 n Your doctor should show you how your child should use Albuterol sulfate Inhalation Aerosol.Each canister of Albuterol sulfate Inhalation Aerosol contains 200 puffs of medicine.
The albuterol inhalation solution (eg, Accuneb®) should be used with a jet nebulizer that is connected to an air compressor with good air flow. In addition, beta-agonists have been 154 reported to produce ECG changes, such as flattening of the T wave, prolongation 155 of the QTc interval, and ST segment depression. Keep out of reach of children.Inhalation Aerosol inhaler and all medicines out of the reach of children.We comply with the HONcode standard for trustworthy health information - THE MOUTHPIECE SHOULD BE WASHED, SHAKEN TO REMOVE EXCESS WATER, AND AIR DRIED THOROUGHLY AT LEAST ONCE A WEEK.
Store at 20°C to 25°C (68°F to 77°F).
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