Pyrazinamide is a medication used to treat tuberculosis. PZA has effective bactericidal properties.
in case of consumer and professional uses). The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). Pyrazinamide: 500 mg: Substance active : Pyrazinamide. 201610637076], China. Clipboard, Search History, and several other advanced features are temporarily unavailable. Taylor & Francis Substances indicated, in 2009, as being intended to be registered by at least one company in the EEA. Free PMC article The work was also supported by Chongqing Scientific & Technological Innovation Special Project of Social Undertakings and People's Livelihood Guarantee [No. Please enable it to take advantage of the complete set of features! Pyrazinamide (PZA) is an antibiotic with specific effectiveness against Mycobacterium tuberculosis. For medical information relating to Covid-19, please consult the
Unable to load your delegates due to an error Substances listed in the EINECS, ELINCS, or NLP inventories. Harmonisation is based on the substance’s physical, toxicological and eco-toxicological hazard assessment.
Registration, Evaluation, Authorisation and Restriction of Chemicals Chemical Agents Directive and Carcinogens or Mutagens Directive EC Inventory, C&L Inventory, Pre-Registration process ; Moffat, A.C., Gas-liquid chromatographic retention indices of 1318 substances of toxicological interest on SE-30 or OV-1 stationary phase, J. Despite 50 years of use, ethambutol has been linked to clinically apparent liver injury in only a few case reports. 2009 Dec;44(12):4954-9. doi: 10.1016/j.ejmech.2009.08.009. In addition, ethambutol is a rare cause of acute, symptomatic liver injury.
Synonym: Pyrazinamide, Pyrazinoic acid amide CAS Number 98-96-4. Epub 2018 May 12.Bouz G, Juhás M, Niklová P, Janďourek O, Paterová P, Janoušek J, Tůmová L, Kovalíková Z, Kastner P, Doležal M, Zitko J.Molecules. Please upgrade your Internet Explorer to a newer version.This website uses cookies to ensure you get the best experience on our websites. Their structures were confirmed by The ‘Hazard classification’ and labelling section uses the If the substance is covered by more than one CLH entry (e.g.
Pyrazinamide : liste des médicaments contenant cette substance. We curated 610 pncA mutations with high confidence experimental and clinical information on pyrazinamide susceptibility. Molecular Weight 123.11 . The molecular consequences of each mutation on protein stability, conformation, and interactions … 14XYY020], Chongqing General Research Project of Basic Science & Frontier Technology [No. The molecular structure is based on structures generated from information available in ECHA’s databases. 2020 May 28;25(11):2521. doi: 10.3390/molecules25112521.Med Chem Res. These notifications can be provided by manufacturers, importers and downstream users. Pyrazinamide plays an important role in tuberculosis treatment; however, its use is complicated by side-effects and challenges with reliable drug susceptibility testing. Information on applicable regulatory frameworks is also automatically generated and may not be complete or up to date. Pyrazinamide (PZA) is an antibiotic with specific effectiveness against Mycobacterium tuberculosis. A list of substances for which classification and labelling data have been notified to ECHA by manufacturers or importers. 2011;17(32):3506-14. doi: 10.2174/138161211798194477.Grill B, Glänzer M, Schwab H, Steiner K, Pienaar D, Brady D, Donsbach K, Winkler M.Molecules. We proposed to use information on how variants were likely to affect the 3D structure of pncA to identify variants likely to lead to pyrazinamide resistance. © Royal Society of Chemistry 2020ass: Standard non-polar; Column type: Other; CAS no: 98964; Active phase: Methyl Silicone; Data type: Normal alkane RI; Authors: Ardrey, R.E.
It was also … 215–540–4, is covered by three harmonisations: 005–011–00–4; 005–011–01–1 and 005–011–02–9), CLH information cannot be displayed in the InfoCard as the difference between the CLH classifications requires manual interpretation or verification.
So far, there has been no evidence …
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