In these patients, alternative pharmacological approaches would seem prudent.You must have JavaScript enabled to enjoy a limited number of articles over the next 360 days. Traditionally, the drug is used to treat inflammation and swelling in patients suffering from allergic reactions. This is why all information is available free of charge and without the need to sign-up or log-in. Background: Dexamethasone has an established role in decreasing postoperative nausea and vomiting (PONV); however, the optimal dexamethasone dose for reducing PONV when it is used as a single or combination prophylactic strategy has not been clearly defined.

My doctor also gave me a pill for indigestion. Clinical Oncology Alert 1998-10-01 Although no short-term toxicity was apparent, there remains concern for those receiving weekly chemotherapy in whom repeated injection of a glucocorticoid, especially at higher doses, might have accumulated toxicity. Nausea can be acute and short-lived, or it can be prolonged. It works by stopping the white blood cells, which are the … in an outpatient infusion center before chemotherapy to prevent nausea and vomiting. It is classed as a glucocorticoid, which is a type of steroid. Methods We … The highest dose selected (20 mg) was most effective. When a medicine is given to prevent nausea and vomiting, it is known as prophylaxis, or prophylactic therapy.Dexamethasone is usually given by mouth or intravenously (I.V.) Doctors use dexamethasone for nausea despite the fact that the drug isn’t an anti-emetic. Rather, it enhances the anti-nausea action of Zofran. If Zofran fails to bring nausea under complete control, Decadron can be added to help Zofran. The Dexamethasone 4mg dose -1 pill in the morning, did the trick. The material provided by ChemoExperts is NOT all-inclusive and is for informational (educational) purposes only. The highest tested dose (20 mg) administered in conjunction with ondansetron (8 mg) was most successful in reducing both nausea and vomiting. February 15, 2012 at 11:44 pm #57790. kathyb. In fact, one curious observation was that the dose effect disappeared when examining patients who received high-dose cisplatin (e.g., doses > 90 mg/mAnother question that remains to be answered is the role of dexamethasone in drug regimens with less emetogenic potential.

The drug is not naturally occurring, like many steroids, but is made synthetically. I could eat anything, and wasn't tired.

Complete protection from nausea and vomiting was achieved in 69.2% and 60.9% of patients, respectively, who received 4 mg of dexamethasone, by 69.1% and 61.0% of those who received 8 mg, by 78.5% and 66.9% of those who received 12 mg, and by 83.2% and 71.0% of those who received 20 mg of dexamethasone. Medscape - Anti-inflammatory-specific dosing for Decadron, Dexamethasone Intensol (dexamethasone), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Goals of dexamethasone (Decadron ®) therapy: Dexamethasone is commonly given on a scheduled basis to prevent nausea and vomiting.

Use: For prophylaxis and treatment of chemotherapy induced nausea and vomiting. Ondansetron (8 mg) was given to all patients 30 minutes before cisplatin. Dexamethasone may also need to be taken at home after chemotherapy for two or three days to help prevent delayed nausea and vomiting.Dexamethasone is typically given with each planned chemotherapy treatment. When prolonged, it is a debilitating symptom. Patients (n = 531) were randomized to receive either 4, 8, 12, or 20 mg of dexamethasone administered by 15-minute IV infusion 45 minutes before cisplatin. Nausea (and vomiting) can be psychological or physical in origin.A Complete Blood Count (CBC) is a frequently ordered blood test that tells clinicians the status of your: A Comprehensive Metabolic Panel (CMP) is a frequently ordered blood test that tells clinicians the status of your: We do our best to provide the highest quality, current information, because we too have had family and friends with cancer. Dexamethasone is designed to help prevent both early and delayed nausea and vomiting caused by chemotherapy.Dexamethasone is commonly given on a scheduled basis to prevent nausea and vomiting. If you are diabetic, you may need to adjust medications used to lower blood sugar while taking dexamethasone.For Branded medications (may be available for generic medications too), check with the manufacturer to determine if a co-pay card is offered and if it could reduce your monthly copay.Nausea is the sensation that there is a need to vomit.

It is designed to help you make more informed decisions about your healthcare and ask more detailed questions of your healthcare provider(s). Although there has been convincing clinical experience with dexamethasone as an anti-emetic agent, the optimal dose has not been clearly defined. I tried other nausea medicines that weren't very effective, or made me very drowsy. I know I can't stay on it for very long, but I hope it will be OK for the next 9 weeks I have left of Chemo.” Here’s what our medical oncologist said about Decadron: Decadron doesn’t control nausea in and by itself.

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