Name /bks_53161_deglins_md_disk/efavirenz 02/12/2014 02:17PM Plate # 0-Composite pg 1 # 1 PDF Page #1 Canadian drug name. It reduces the viral load (plasma HIV-RNA) The active form of tenofovir persists in HIV-infected cells for prolonged periods, thus, it results in sustained inhibition of HIV replication. Nursing Implications. To learn more about possible side effects of tenofovir DF, read the drug label or You can report side effects to FDA at 1-800-FDA-1088 (1-800-332-1088) or The above Patient Version drug summary is based on the following FDA label(s): Provided in collaboration with NIH’s Office of AIDS Research.Get the latest public health information from CDC: What are the most important things to know about tenofovir disoproxil fumarate? of HIV replication. lactation. People who are unable to swallow the tablets whole may take the oral powder. Mix the oral powder with soft foods that can be swallowed without chewing, such as applesauce, baby food, or yogurt.Always take tenofovir DF in combination with other HIV medicines.If you take too much tenofovir DF, contact your health care provider or local poison control center (1-800-222-1222) right away, or go to the nearest hospital emergency room.For more information on how to take tenofovir DF, see the If you miss a dose of tenofovir DF, take the missed dose as soon as you remember it.
Thera-peuticEffects:Slowed progression of HIV infection and decreased occurrence of sequelae. Tenofovir is a potent inhibitor of retroviruses, including HIV-1. Many side effects from HIV medicines, such as nausea or occasional dizziness, are manageable.
Increased CD4 cell count and decreased viral load. Lab tests: Obtain baseline and periodic liver and kidney function tests, routine blood chemistry, and CBC. Assessment & Drug Effects. While taking tenofovir DF, it is important to keep all of your appointments with your health care provider.Tenofovir disoproxil fumarate (tenofovir DF) is a prescription medicine approved by the U.S. HIV medicines can't cure HIV/AIDS, but taking HIV medicines every day helps people with HIV live longer, healthier lives.
(7.2) Coadministration decreases atazanavir concentrations. It reduces the viral load (plasma HIV-RNA), and CD4 counts. Tenofovir side effects. When coadministered with VIREAD, use atazanavir given with ritonavir. Contact your health care provider right away if you have any of the following symptoms that could be signs of lactic acidosis: It may be active against nucleoside-resistant HIV strains.The active form of tenofovir persists in HIV-infected cells for prolonged periods, thus, it results in sustained inhibition Coadministration of VIREAD with certain HIV-1 protease inhibitors Dose reduction and close monitoring for didanosine toxicity are warranted. These include a buildup of lactic acid in the blood (lactic acidosis), severe liver problems, and new or worsening kidney problems, including kidney failure.. -The effects of tenofovir alafenamide in the nursing infant are unknown; tenofovir disoproxil has been used without apparent harmful effects in the nursing infant.
Genetic Implication. Unknown if tenofovir DF affects milk production or has effects on the breastfed child. Active drug (tenofovir) is phosphorylated intracellularly; tenofovir diphosphate in-hibits HIV reverse transcriptase resulting in disruption of DNA synthesis.
Do not take two doses at the same time to make up for a missed dose.Tenofovir DF may cause side effects. Tenofovir disoproxil fumarate increases didanosine concentrations. But if it is almost time for your next dose, skip the missed dose and just take your next dose at the regular time.
Tenofovir is a potent inhibitor of retroviruses, including HIV-1. Monitor weight, temperature, respiratory status with chest x-ray throughout therapy. See the ClinicalInfo fact sheet on Other possible side effects of tenofovir DF include:Tell your health care provider if you have any side effect that bothers you or that does not go away.These are not all the possible side effects of tenofovir DF. It may be active against nucleoside-resistant HIV strains. In combination with other antiretrovirals for the treatment of HIV.Hypersensitivity to tenofovir; hepatitis; lactic acidosis; concurrent administration of nephrotoxic agents, renal failure; Tenofovir oral tablet is a prescription medication used to treat HIV and chronic hepatitis B infection.
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