The possibility that patients who become sensitized to topical clindamycin also may be sensitive to systemic clindamycin or lincomycin should be considered.Urticaria, rash, application-site pain, and pruritus occur rarely in patients receiving intravaginal clindamycin.Adverse GI effects including diarrhea, and less frequently, abdominal pain, bloody diarrhea, and colitis have been reported following topical application of clindamycin. We comply with the HONcode standard for trustworthy health information - Sur la base de lApplication: Men, Women. Treatment-related vaginal and nonvaginal candidiasis (moniliasis) and vaginitis (e.g., vulvovaginal disorder, vaginal discharge, vaginitis, vaginal infections) were reported in about 3-3.5% of nonpregnant women who received the drug in clinical studies for the treatment of bacterial vaginosis. Results of clinical studies indicate that combination therapy results in a reduction in total lesion counts of 50-70%.Clindamycin is used intravaginally as a vaginal cream or suppository or orally for the treatment of bacterial vaginosis (formerly called Bacterial vaginosis is a noninflammatory vaginal syndrome characterized by replacement of the normal vaginal flora (predominantly hydrogen peroxide-producing Gram stain results consistent with a diagnosis of bacterial vaginosis include markedly reduced or absent Goals of treatment and recommended therapy for bacterial vaginosis differ for nonpregnant versus pregnant women. In vivo studies indicate that clindamycin penetrates comedones following topical application. Do not expose to heat or store at temperature above 120°F (49°C).Patients should wash their hands after applying Clindamycin Phosphate Foam, 1%.Clindamycin Phosphate Foam, 1% may cause irritation such as erythema, scaling, itching, burning, or stinging. Benzoyl peroxide is absorbed by the skin where it is converted to benzoic acid; less than 2% of the dose of benzoyl peroxide enters systemic circulation as benzoic acid.Clindamycin phosphate is absorbed systemically following intravaginal application of the drug as a vaginal cream or suppositories. Candidal infection (including vaginal or nonvaginal candidiasis and fungal infection, either symptomatic or confirmed by culture) has been reported in about 3 or 9-11% of nonpregnant patients receiving intravaginal clindamycin suppositories or cream, respectively.The most frequent adverse effects of topical therapy with clindamycin phosphate 1% gel, lotion, or solution are dryness of the skin and erythema. CDAD, including fulminant pseudomembranous colitis, have been attributed to the use of intravaginal clindamycin.Dizziness, headache, flank pain, localized edema, and vertigo reportedly occur in less than 1% of patients receiving clindamycin phosphate vaginal cream or suppositories. The can is pressurized with a hydrocarbon (propane/butane) propellant.This Patient Information has been approved by the U.S. Food and Drug Administration.The following image is a placeholder representing the product identifier that is either affixed or imprinted on the drug package label during the packaging operation.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Table 1: Adverse Reactions Occurring in ≥ 1% of SubjectsSee FDA-Approved patient labeling (Patient Information)Important: For skin use only. The clindamycin phosphate solution is then added to the benzoyl peroxide gel provided by the manufacturer and stirred for about 1-1.5 minutes until the gel appears homogeneous.Clindamycin phosphate is administered intravaginally as a vaginal cream containing 2% clindamycin or as a vaginal suppository containing 100 mg of the drug.

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