Cerner Multum, Inc. "Canadian Product Information."
No specific antidote is available for overdose with PREZCOBIX.
Defective and dangerous drugs fall under product liability laws in the United States. Call your doctor for medical Serious side effects of Depakote include: liver injury (symptoms include yellowing skin and eyes, general feeling of being unwell, weakness, swelling in the face, loss of appetite and vomiting), pancreatitis (symptoms include weight loss, nausea, vomiting and severe abdominal pain), and
Inform patients not to alter the dose of PREZCOBIX or discontinue therapy with PREZCOBIX without consulting their physician [see Inform patients that drug-induced hepatitis (e.g., acute hepatitis, cytolytic hepatitis) and liver injury, including some fatalities, could potentially occur with PREZCOBIX. Call your doctor at once if you have: high blood sugar - increased thirst, increased urination, … It selectively inhibits the cleavage of HIV-1 encoded Gag-Pol polyproteins in infected cells, thereby preventing the formation of mature virus particles.Cobicistat is a selective, mechanism-based inhibitor of cytochromes P450 of the CYP3A subfamily. Because these events have been reported voluntarily during clinical practice, estimates of frequency cannot be made and causal relationships between HIV PI therapy and these events have not been established.Redistribution/accumulation of body fat, including central obesity, dorsocervical fat enlargement (buffalo hump), peripheral wasting, facial wasting, breast enlargement, and “cushingoid appearance” have been observed in patients receiving antiretroviral therapy. Therefore, co-administration of PREZCOBIX with drugs that are primarily metabolized by CYP3A and/or CYP2D6 or are substrates of P-gp, BCRP, MATE1, OATP1B1 or OATP1B3 may result in increased plasma concentrations of such drugs, which could increase or prolong their therapeutic effect and can be associated with adverse events (see Darunavir is metabolized by CYP3A. Visit the Copyright © 2020 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. These are not all of the possible side effects of PREZCOBIX. The effect of severe hepatic impairment on the pharmacokinetics of darunavir has not been evaluated [see Cobicistat is primarily metabolized by the liver. Darunavir and cobicistat are present in the milk of lactating rats (see Additional or alternative (non-hormonal) forms of contraception should be considered when estrogen-containing contraceptives are co-administered with PREZCOBIX.
Do not give PREZCOBIX to other people, even if they have the same symptoms that you have. Cerner Multum, Inc. "UK Summary of Product Characteristics." Treatment of overdose with PREZCOBIX consists of general supportive measures including monitoring of vital signs and observation of the clinical status of the patient. Tell your doctor if you have:
Cerner Multum, Inc. "UK Summary of Product Characteristics." See cobicistat full prescribing information for clinical trial information on adverse reactions reported with cobicistat.One single arm clinical trial was conducted with darunavir and cobicistat administered as single entities in 313 HIV-infected subjects. advice about side effects. Cerner Multum, Inc. "Australian Product Information." Depakote (divalproex sodium)." Discontinue PREZCOBIX immediately if signs or symptoms of severe skin reactions develop. Be ready to tell or show what was Depakote and Depakene can cause serious side effects, including: 1.Serious liver damage that can cause death, especially in children younger than 2 years old.
doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Common side effects of Prezcobix include: diarrhea, nausea, rash, headache, abdominal pain, vomiting, and changes in body fat distribution.
Call your doctor for medical advice about side effects.
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