Renal transplantation is the treatment of choice for most patients with end stage renal disease. We found no differences in effect for these outcomes (Additional results of meta-analysis: complications and adverse reactionsThe most consistent definition used to report disturbance of glucose metabolism was “new diabetes mellitus,” defined as a requirement for insulin treatment for ≥ 30 days in previously non-diabetic patients. 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mofetil/steroids in renal transplantation.One-year follow-up of a Brazilian randomized multicenter study comparing tacrolimus versus cyclosporine in kidney transplantation.A three arm study comparing immediate tacrolimus therapy with ATG induction therapy followed by either tacrolimus or cyclosporine in adult renal transplant recipients.One year evolution of bone mineral density in kidney transplant recipients receiving tacrolimus versus cyclosporine.Changes in lipid metabolism and effect of simvastatin in renal transplant recipients induced by cyclosporine or tacrolimus.Randomized trial of tacrolimus (Prograf) in combination with azathioprine or mycophenolate mofetil versus cyclosporine (Neoral) with mycophenolate mofetil after cadaveric kidney transplantation.Phase II FK 506 multicenter concentration control study: one-year follow-up.Randomized trial of tacrolimus in combination with mycophenolate mofetil versus cyclosporine with mycophenolate mofetil in cadaveric renal transplant recipients with delayed graft function.European Tacrolimus vs Ciclosporin Microemulsion Renal Transplantation Study GroupEfficacy and safety of tacrolimus compared with ciclosporin microemulsion in renal transplantation: a randomised multicentre study.Multicenter randomized trial comparing tacrolimus (FK506) and cyclosporine in the prevention of renal allograft rejection: a report of the European Tacrolimus Multicenter Renal Study Group.Prospective randomised study comparing tacrolimus (Prograf) and cyclosporin (Neoral) as primary immunosuppression in cadaveric renal transplants at a single institution: interim report of the first 80 cases.Arterial hypertension in renal transplant recipients treated with tacrolimus or cyclosporine-neoral.A comparison of tacrolimus (FK506) and cyclosporine for immunosuppression after cadaveric renal transplantation.Pronounced renal vasoconstriction and systemic hypertension in renal transplant patients treated with cyclosporin A versus FK 506.A prospective randomized trial comparing the efficacy of tacrolimus versus cyclosporine in black recipients of primary cadaveric renal transplants.Tacrolimus- vs cyclosporin microemulsion-based treatment in renal transplantation: comparison with third month protocol biopsies [abstract].Randomized trial of tacrolimus versus cyclosporin microemulsion in renal transplantation.Glucose metabolism in the first 3 years after renal transplantation in patients receiving tacrolimus versus cyclosporine-based immunosuppression.Tacrolimus vs CyA Neoral in combination with MMF and steroids after cadaveric renal transplantation.Effects of three immunosuppressive regimens on CD4 helper function, B cell monocyte and cytokine responses in renal transplant recipients: 4-month follow-up of a prospective randomized study.Effect of acute rejection on expression of fibrosis associated genes in renal transplant recipients.Tacrolimus/”low-dose” mycophenolate mofetil versus microemulsion cyclosporine/”low-dose” mycophenolate mofetil after kidney transplantation—1-year follow-up of a prospective, randomized clinical trial.Clinical experience with Prograf (tacrolimus, FK 506) in Chinese patients after renal transplantation.Pediatric renal transplantation: a review of the UNOS data.Inferior outcome of two-haplotype matched renal transplants in blacks: role of early rejection.Problems and limitations in conducting systematic reviews.Practical clinical trials: increasing the value of clinical research for decision making in clinical and health policy.Evolution of endpoints for renal transplant outcome.Biomarkers and surrogate endpoints in renal transplantation: present status and considerations for clinical trial design.How should meta-regression analyses be undertaken and interpreted?Nephrotoxicity of immunosuppressive drugs: long-term consequences and challenges for the future.Late deterioration of organ transplants: a problem in injury and homeostasis.The natural history of chronic allograft nephropathy.Calcineurin inhibitor nephrotoxicity: longitudinal assessment by protocol histology.Anti-Lymphocyte Antibody Induction Therapy Study GroupIndividual patient- versus group-level data meta-regressions for the investigation of treatment effect modifiers: ecological bias rears its ugly head.Tacrolimus versus cyclosporin for immunosuppression in renal transplantation: meta-analysis of randomised trials.New onset diabetes mellitus in patients receiving calcineurin inhibitors: a systematic review and meta-analysis.Immunosuppressive therapy for renal transplantation in adults.Tacrolimus versus ciclosporin as primary immunosuppression for kidney transplant recipients: meta-analysis and meta-regression of randomised trial data
doi: 10.1002/14651858.CD008842.pub2.Masson P, Henderson L, Chapman JR, Craig JC, Webster AC.Cochrane Database Syst Rev.
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