Itraconazole is an inhibitor of the drug transporters P-glycoprotein and breast cancer resistance protein (BCRP).
In addition, coadministration with colchicine, fesoterodine and solifenacin is contraindicated in subjects with varying degrees of renal or hepatic impairment, and coadministration with eliglustat is contraindicated in subjects that are poor or intermediate metabolizers of CYP2D6 and in subjects taking strong or moderate CYP2D6 inhibitors. Also tell your doctor about any other medical conditions you have had, especially heart, lung, liver or kidney conditions; or if you have cystic fibrosis, or have had an allergic reaction to itraconazole capsules or any other antifungal medicines.Taking itraconazole capsules with certain other medicines may lead to serious or life-threatening medical problems.
II: 1991–96Endemic blastomycosis in Mississippi: epidemiological and clinical studiesSymposium on infectious complications of neoplastic disease (Part II). A pharmacokinetic study using a single 200-mg oral dose of itraconazole was conducted in three groups of patients with renal impairment (uremia: n=7; hemodialysis: n=7; and continuous ambulatory peritoneal dialysis: n=5). It is recommended that patients with impaired hepatic function be carefully monitored when taking itraconazole. If you have had heart, lung, liver, kidney or other serious health problems, ask your doctor if it is safe for you to take itraconazole capsules.Anyone can have a fungal nail infection, but it is usually found in adults.
L'administration de cisapride (qui n'est plus commercialisé en France) chez le nourrisson allaité peut conduire à une interaction médicamenteuse et contre-indique l'allaitement. (See -glycolic) acid nanoparticles for improved antifungal activity Renal excretion of itraconazole and the active metabolite hydroxy-itraconazole account for less than 1% of an intravenous dose.
It is recommended that liver function monitoring be done in patients with pre-existing hepatic function abnormalities or those who have experienced liver toxicity with other medications.
Itraconazole capsules are available containing 100 mg of itraconazole, with a pink transparent body printed 100 and blue cap your fungal nail infection.Itraconazole goes into your bloodstream and travels to the source of the infection underneath the nail so that it can fight the A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in superficial and systemic mycosesOptimisation of itraconazole therapy using target drug concentrationsA pharmacokinetic study of intravenous itraconazole followed by oral administration of itraconazole capsules in patients with advanced human immunodeficiency virus infectionProphylaxis of fungal infections with itraconazole during remission‐induction therapyEndoscopic and histologic diagnosis of intestinal graft‐versus‐host disease after marrow transplantationEffect of cyclodextrin on the pharmacology of antifungal oral azolesThe clinical pharmacokinetics of itraconazole: an overviewItraconazole pharmacokinetics in the female genital tract: plasma and tissue levels in patients undergoing hysterectomy after a single dose of 200 mg of itraconazolePharmacokinetic profile of orally administered itraconazole in human skinItraconazole penetrates the nail via the nail matrix and the nail bed – an investigation in onychomycosisEnhanced bioavailability of itraconazole in hydroxypropyl‐β‐cyclodextrin solution versus capsules in healthy volunteersEffect of food on the pharmacokinetics of a new hydroxypropyl‐beta‐cyclodextrin formulation of itraconazoleFood interaction and steady‐state pharmacokinetics of itraconazole oral solution in healthy volunteersThe pharmacokinetic rationale behind intravenous itraconazoleOral and intravenous itraconazole for systemic fungal infections in neutropenic haematological patients: meeting reportDevelopment of interpretive breakpoints for antifungal susceptibility testing: conceptual framework and analysis of Itraconazole solution: higher serum drug concentrations and better clinical response rates than the capsule formulation in acquired immunodeficiency syndrome patients with candidosisPharmacokinetics of itraconazole following oral administration to normal volunteersThe pharmacokinetics of oral itraconazole in AIDS patientsShort report: the absorption of fluconazole and itraconazole under conditions of low intragastric acidityAlterations in gastric acidity in patients infected with human immunodeficiency virusLack of interaction of antacid drug omeprazole on the bioavailability of itraconazole oral solutionPharmacokinetics of itraconazole (oral solution) in two groups of human immunodeficiency virus‐infected adults with oral candidiasisRandomized trial of itraconazole oral solution for oropharyngeal candidiasis in HIV/AIDS patientsPharmacokinetics of itraconazole oral solution in allogeneic bone marrow transplant patients receiving total body irradiationMultiple dose pharmacokinetics of an oral solution of itraconazole in autologous bone marrow transplant recipientsMultiple dose pharmacokinetics of an oral solution of itraconazole in patients receiving chemotherapy for acute myeloid leukaemiaItraconazole oral solution as prophylaxis for fungal infections in neutropenic patients with hematologic malignancies: a randomized, placebo‐controlled, double‐blind, multicenter trialConcentrations in plasma and safety of 7 days of intravenous itraconazole followed by 2 weeks of oral itraconazole solution in patients in intensive care unitsPharmacokinetics and safety of seven days’ intravenous itraconazole followed by two weeks’ oral itraconazole solution in patients with haematological malignancyItraconazole for treatment of oral candidosis in pediatric cancer patientsFungal colonization and infection in children with acute leukemia and lymphoma during induction therapyRepeated‐dose pharmacokinetics of an oral solution of itraconazole in infants and childrenSafety and pharmacokinetics of fluconazole in children with neoplastic diseasesDose adjustment and cost of itraconazole prophylaxis in lung transplant recipients receiving cyclosporine and tacrolimus (FK506)Treatment of fluconazole‐refractory oropharyngeal candidiasis with itraconazole oral solution in HIV‐positive patientsA randomized controlled trial of itraconazole versus fluconazole for the prevention of fungal infections in patients with haematological malignanciesProphylaxis of fungal infections in haematological malignancy: a double blind trial comparing itraconazole oral solution to amphotericin B capsulesItraconazole (IT) compared with amphotericin B (AMB) as empirical therapy for persistent fever of unknown origin (FUO) in neutropenic patients (PTS)Effects of itraconazole in the treatment of oral candidosis in HIV patients, a double‐blind, double‐dummy, randomized comparison with fluconazoleEffect of itraconazole in the treatment of oral candidosis and Candida oesophagitis in HIV+ patients.
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