They studied 290 breast cancer patients undergoing treatment with Tamoxifen or another of the aromatase inhibitor drugs. Below are a number of medications and supplements that may interact with tamoxifen. 26 Jul 2020 6:03 AM. Tamoxifen is a synthetic non-steroidal ant estrogen.

Or maybe we could just get our vitamin D levels checked before starting the aromatase inhibitors and, if they are found to be suboptimal, start supplementing with vitamin D3. Please enable it to take advantage of the complete set of features! It was suggested to study the role of vitamin C in alte- ration of enzymes responsible of energy metabolism induced by administration of tamoxifen to mouse. Vitamin D has been shown to inhibit the growth of tamoxifen-resistant breast cancer cells in the laboratory and resveratrol has been found to reduce their proliferation. Things like terrible hot flashes, joint pain, muscle pain, carpal tunnel syndrome and even trigger finger (a painful painful condition that causes the fingers or thumb to catch or lock when bent, it happens when the tendons in the finger or thumb become inflamed) are quite common side effects.A chance conversation with one of my subscribers this week led me to do some research on vitamin D because she shared with me that she was on Tamoxifen and had been recommended to take some higher-than-normal doses of vitamin D for her joint pain, and it was helping!Vitamin D3 is one of the supplements I already recommend because it has great benefits for breast health. Unable to load your collection due to an error Medications that should be avoided with tamoxifen include: [2] Aromatase Inhibitor-Induced Arthralgia – A Review — https://academic.oup.com/annonc/article/24/6/1443/180703Interestingly I reacted to tamoxifen, arimidex and ground flax the same way.

tamoxifen and vitamin c. Posted by Tabitha29. I am very surprised to hear that you reacted to flaxseed. PRE menopausal ovaries are struggling to still produce estrogen and so you still make it and it needs to be kept away from any receptors, so any cells will die off. This, however, should be decided in consult with your physician. All of the patients were given 800 iu daily of vitamin D, and those who were especially deficient also got an additional 16,000 iu every two weeks.Of the women who were pain-free at baseline, those who reached serum levels of 40 ng/ml were 50% less likely to experience drug-associated joint pain than those who remained vitamin D deficient. High-dose vitamin E supplements may interact with tamoxifen. 2019 May;40(5):699-709. doi: 10.1038/s41401-018-0158-8. Of note, research has found that your vitamin D level may be linked to the effectiveness of tamoxifen and that levels of endoxifen tend to be significantly higher in women in the summer months.Get honest information, the latest research, and support for you or a loved one with breast cancer right to your inbox.Penn State Health  Milton S. Hershey Medical Center. Perhaps we could have a conversation about this. It would be my pleasure and my honor to assist you. Sathiavelu J, Senapathy GJ, Devaraj R, Namasivayam N.J Pharm Pharmacol. I am confused whether flax and soy products should be avoided or not. et al. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. at 4°C. Teft, WA. Tamoxifen (TAM) may act on estrogen receptors (ER) located in the plasma membrane. It was concluded that vitamin C may prevent tamoxifen-induced testes toxicity in mice. The present results also, showed that significant reduction in glycogen, total protein, total cholesterol, uric acid, urea, and creatinine in treated mice as compared to the normal healthy control group. At baseline, 90% of the women had serum vitamin D levels under 30 ng/ml, which is considered a deficiency. It is also being studied for other types of cancer. The information on these interactions is relatively new (tamoxifen was approved in 1998, but interactions were not noted until later on) and studies are currently in progress looking at this issue in greater depth. If you have been prescribed tamoxifen for breast cancer, you've likely heard that it can interact with some other medications.

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