Avoid freezing. Timolol Maleate Ophthalmic Gel Forming Solution should not be used alone in the treatment of angle-closure glaucoma.While taking beta-blockers, patients with a history of atopy or a history of severe anaphylactic reactions to a variety of allergens may be more reactive to repeated accidental, diagnostic, or therapeutic challenge with such allergens. timolol).In patients with angle-closure glaucoma, the immediate objective of treatment is to reopen the angle. Hold the dropper directly over your eye and place one drop in your eye. Most people with Tell your doctor right away if any of these unlikely but serious side effects occur: Tell your doctor right away if any of these rare but very serious side effects occur: Seek immediate medical attention if any of these rare but very serious side effects occur: This is not a complete list of possible side effects. The effect of timolol in lowering intraocular pressure was evident for 24 hours with a single dose of Timolol Maleate Ophthalmic Gel Forming Solution. The gel forming solution contains a purified anionic heteropolysaccharide derived from gellan gum. The concomitant use of two topical beta-adrenergic blocking agents is not recommended.Caution should be used in the coadministration of beta-adrenergic blocking agents, such as Timolol Maleate Ophthalmic Gel Forming Solution, and oral or intravenous calcium antagonists because of possible atrioventricular conduction disturbances, left ventricular failure, and hypotension. Keep using this medication even if you feel well. Denn jeder Mensch reagiert unterschiedlich auf Medikamente. Preservative: benzododecinium bromide 0.012%The gel forming solution contains a purified anionic heteropolysaccharide derived from gellan gum. A slight reduction in resting heart rate was observed in some patients receiving Timolol Maleate Ophthalmic Gel Forming Solution 0.5% (mean reduction 24 hours post-dose 0.8 beats/minute, mean reduction 2 hours post-dose 3.8 beats/minute). Do not store in the bathroom. You do not need to shake the container more than once.Tilt your head back, look upward and pull down the lower eyelid to make a pouch. This medication is for use in the eye (s), usually one drop in the affected eye (s) once a day, or as directed by your doctor. Doses of 1000 mg/kg/day (142,000 times the systemic exposure following the maximum recommended human ophthalmic dose) were maternotoxic in mice and resulted in an increased number of fetal resorptions. (See When patients have been switched from therapy with timolol maleate ophthalmic solution administered twice daily to Timolol Maleate Ophthalmic Gel Forming Solution administered once daily, the ocular hypotensive effect has remained consistent.Timolol Maleate Ophthalmic Gel Forming Solution is a colorless to nearly colorless, slightly opalescent, and slightly viscous solution.No. Due to the physical characteristics of the formulation, there was a higher incidence of transient blurred vision in patients administered Timolol Maleate Ophthalmic Gel Forming Solution. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. Use Timolol Maleate Ophthalmic Gel Forming Solution as prescribed by your doctor.If you have any questions about the use of Timolol Maleate Ophthalmic Gel Forming Solution, please consult your doctor. If you notice other effects not listed above, contact your doctor or pharmacist.Call your doctor for medical advice about side effects. However, in some studies, a slight increase in outflow facility was also observed.Beta-adrenergic receptor blockade reduces cardiac output in both healthy subjects and patients with heart disease. In patients with impaired cardiac function, coadministration should be avoided.Close observation of the patient is recommended when a beta blocker is administered to patients receiving catecholamine-depleting drugs such as reserpine, because of possible additive effects and the production of hypotension and/or marked bradycardia, which may result in vertigo, syncope, or postural hypotension.The concomitant use of beta-adrenergic blocking agents with digitalis and calcium antagonists may have additive effects in prolonging atrioventricular conduction time.Potentiated systemic beta-blockade (e.g., decreased heart rate, depression) has been reported during combined treatment with CYP2D6 inhibitors (e.g. 817 – Timolol Maleate Ophthalmic Gel Forming Solution, 0.5% timolol equivalent, is supplied in a white, translucent, HDPE plastic ophthalmic dispenser with a controlled drop tip and a white polystyrene cap as follows:OPHTHALMIC MEDICATIONS, IF HANDLED IMPROPERLY, CAN BECOME CONTAMINATED BY COMMON BACTERIA KNOWN TO CAUSE EYE INFECTIONS. Some patients receiving beta-adrenergic receptor blocking agents have experienced protracted, severe hypotension during anesthesia. Storage. Timolol has been reported rarely to increase muscle weakness in some patients with myasthenia gravis or myasthenic symptoms.Patients should be instructed to avoid allowing the tip of the dispensing container to contact the eye or surrounding structures.Patients should also be instructed that ocular solutions, if handled improperly or if the tip of the dispensing container contacts the eye or surrounding structures, can become contaminated by common bacteria known to cause ocular infections.

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