what are the most common side effects of topamax


Hyperammonemia with and without encephalopathy has been reported in the post-marketing period. In a pooled analysis of placebo-controlled studies of approved and unapproved indications, bleeding was more frequently reported as an adverse reaction for TOPAMAX® than for placebo (4.5% versus 3.0% in adult patients, and 4.4% versus 2.3% in pediatric patients). Topamax may cause temporary changes to your digestive system. Common side effects of Topamax include: tiredness, drowsiness, dizziness, loss of coordination, tingling of the hands/feet, loss of appetite, bad taste in the mouth, diarrhea, weight loss, confusion, slowed thinking, trouble concentrating or paying attention, nervousness, memory problems, and; speech or language problems. Values below 10 mEq/L have been rarely reported. The adverse reactions associated with discontinuing therapy in the TOPAMAX®-treated patients included paresthesia (7%), fatigue (4%), nausea (4%), difficulty with concentration/attention (3%), insomnia (3%), anorexia (2%), and dizziness (2%).Patients treated with TOPAMAX® experienced mean percent reductions in body weight that were dose-dependent. 2. confusion psychomotor slowing, difficulty with concentration/attention, difficulty with memory, speech, or language problems, particularly word-finding difficulties); psychiatric/behavioral disturbances (e.g. 4. Adverse reactions associated with discontinuing therapy that occurred in more than one TOPAMAX®-treated patient were fatigue (1%), headache (1%), and somnolence (1%).TOPAMAX® is associated with an increased risk for bleeding. This change was not seen in the placebo group. Adverse reactions associated with discontinuing TOPAMAX® included somnolence, dizziness, anxiety, difficulty with concentration or attention, fatigue and paresthesia.In pooled, controlled clinical trials in pediatric patients (2 to 15 years of age) with partial-onset seizures, primary generalized tonic-clonic seizures, or Lennox-Gastaut syndrome, 98 patients received adjunctive therapy with TOPAMAX® at dosages of 5 to 9 mg/kg/day (recommended dose range) and 101 patients received placebo.The most common adverse reactions in the controlled clinical trial that occurred in pediatric patients in the 5 mg to 9 mg/kg/day TOPAMAX® group with an incidence higher (≥ 10 %) than in the placebo group were: fatigue and somnolence (Table 7).Table 7 presents the incidence of adverse reactions that occurred in at least 3% of pediatric patients 2 to 15 years of age receiving 5 mg to 9 mg/kg/day (recommended dose range) of TOPAMAX® and was greater than placebo incidence.None of the pediatric patients who received TOPAMAX® adjunctive therapy at 5 to 9 mg/kg/day in controlled clinical trials discontinued due to adverse reactions.In the four multicenter, randomized, double-blind, placebo-controlled, parallel group migraine clinical trials for the preventive treatment of migraine (which included 35 pediatric patients 12 to 15 years of age), most adverse reactions occurred more frequently during the titration period than during the maintenance period.The most common adverse reactions with TOPAMAX® 100 mg in the clinical trials for the preventive treatment of migraine of predominantly adults that were seen at an incidence higher (≥ 5 %) than in the placebo group were: paresthesia, anorexia, weight loss, taste perversion, diarrhea, difficulty with memory, hypoesthesia, and nausea (see Table 8).Table 8 includes those adverse reactions that occurred in the placebo-controlled trials where the incidence in any TOPAMAX® treatment group was at least 3% and was greater than that for placebo patients.
O 05. Common side effects of Topamax include: tiredness, drowsiness, dizziness, nervousness, numbness or tingly feeling in the hands or feet, coordination problems, diarrhea, weight loss, speech/language problems, changes in vision, sensory distortion, loss of appetite, bad taste in your mouth, confusion,
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Along with its needed effects, topiramate (the active ingredient contained in Some side effects of topiramate may occur that usually Check with your health care professional if any of the following side effects Generally, topiramate-induced metabolic acidosis occurs early in treatment; however, it can occur any time. The incidence was higher in men. Problem Behavior 23. Loss Of Appetite 16. You may report them to the The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.

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