Bare with me cause this is gonna get simple. I can’t get straight answers from about 7 doctors now, so I will have to learn by experience.Hi ken. This has become an economic strategy for the drug companies and a potential disaster for our health. Take? Regulators have followed this line because the definition of statistical significance offers them a rule of thumb, an almost mechanical procedure that takes the place of a judgment call. It seems, at least on the surface of it, that there’s a really low requirement to get someone on a drug but a much higher statistical requirement for withdrawal.
A number of medical academics have attempted to grapple with this, pointing out that current dependence on statistical significance testing has created a “junk epidemiology” in the domain of therapeutics. I went and took tennis lessons, joined a league, and started getting out of bed much easier and an hour earlier.

You don’t. Anybody got any advice.I have just landed in this article as i have taken the decision to stop Imuran after nearly 8 years for my UC when i heard that the coronavirus will be of a greater impact to people with low immune system. I obviously hope my LFTs behave when off meds totally but as l believe, and as a research nurse l have researched my hypothesis, that MY trigger which kicked off my AIH is tonic water (can’t metabolise quinine due to a defective metabolic pathway gene), that keeping tonic out of my diet will stave off a flare. If it did return then yes, I’d return to taking the Imuran as needed.I have been advised to stop taking the azathioprine by my gastro.
It was about 3 and a half years after surgery and I’d been in remission the entire time. So, we’ll see. After 10 years. My take on the second step is to say it might be interesting to try and predict who will relapse based on bloodwork results or genetics or something related to lifestyle and diet. The cancer is related to this medication and we didn’t know it until now. I had to have a pericardial effusion from all the fluid around my heart. I was really worried about the side-effects of coming off and whether it would be affected again if I needed it down the track. On aza I can only workout using fewer weight/resistance and for just a short period (at 40mins I am lightheaded and completely short of breath). I also have joint aches, fatigue, and bad nausea. After 2 1/2 months of flu like symptoms, I developed a large left lung abscess that collapsed the lung and had meCan you quit azathiaprine cold turkey? I stopped taking it 3 months ago. It is not a benign medication, but it is relatively safe, much safer than steroids. I was only on .25 for the first few years as I could not tolerate the drug. All rights reserved. Just recently I read the official “patient information” for the soon-to-be-released diet drugs Belviq and Qsymia. Then count the number of relapses over the next 18 months. I was on steroids and gradually stopped them against the doctors advice. So Louis Lasagna, the first professor of clinical pharmacology in the United States, and later dean of medicine at Tufts University, who introduced randomized controlled trials into drug development, described the approach outlined above as “p-value madness”. I am 67 years old and just spent 2 weeks in ICU after two months of flare up (7 months flare last year and no one could decide what was wrong)…all doctors recommended “take more Imodium.” I think another flare will kill me. Ken, I read you article about the azathioprine withdrawal. I’m still trying to hold down a busy demanding job and doing this every week isn’t really practical. But still wasn’t great knowing i was taking something that’s a carcinogen.I weaned off imuran 2 mos ago.

But I am determined to stay off of this drug and hope that you are able to go into full remission with no prescription drugs at all!15 weeks in I feel better than ever.

This medicine may increase your risk of getting certain types of cancer, especially of the skin, lymph system (lymphoma), or blood (leukemia). There’s probably physicians who have read this paper and they go on prescribing azathioprine even though someone’s been in remission for years.

It seems to deserves some research and thinking at least.The call for an Exit strategy is an absolutely key point. It was passively acknowledged at most. Thank you!I was on Imuran for 10 years for a rare auto-immune disease called Pemphigus Vulgaris.

Have been on it for abou 2 1/2 months and I have horrible side effects. I only take 25mg daily but would like to stop as I’ve been on it a little over 3 years now, wondering if I should only take it every other day, then every 3 days, gradually reducingI came off azathioprine in March, 2019.

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