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It has been determined that HIV-1 is a zoonotic infection likely transmitted in the early 1900s (there were reports in the 1900s of healthy individuals succumbing to opportunistic infections) from butchered chimpanzees infected with SIVcpz. Zidovudine (AZT) which attacks the virus through the enzyme reverse transcriptase 3. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising.

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Protease inhibitors bind to the active site of the protease enzyme and prevent the maturation of the newly produced virions so that they remain non …

They block the function of HIV protease enzymes. 2 months ago

at Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Chris Blair 4/14/2015 HIV-1 PROTEASE INHIBITORS . Dideoxyinosis 3. stavudine 4.

, 10. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Origin – HIV-1 was sequenced to SIV and found that they are similar.

The first members of this class, saquinavir and ritonavir were approved in late 1995-1996. If you continue browsing the site, you agree to the use of cookies on this website. Protease inhibitors are synthetic drugs that inhibit the action of HIV-1 protease, an enzyme that cleaves two precursor proteins into smaller fragments.These fragments are needed for viral growth, infectivity and replication.

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Three other inhibitors namely 1. DRUGS USED FOR AIDS Mainly antiviral drugs like: 1. Your message goes here

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pharmacological perspective Radiation protection,protease inhibition.

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K2010H146037H Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Your message goes here Use of protease inhibitors like Saquinavir, Indinavir and Ritonavir 5. Now customize the name of a clipboard to store your clips. , • Protease inhibitors were the second class of antiretroviral drugs developed. Now customize the name of a clipboard to store your clips. See our Dideoxycytosine 2.

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• Protease inhibitors were designed to mimic the • transition state of protease. If you continue browsing the site, you agree to the use of cookies on this website.

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