The grounds for referral are appended to this report. (PDF/132.28 KB) (PDF/495.21 KB) (PDF/140.26 KB)
(PDF/111.33 KB) (PDF/118.3 KB) (PDF/270.44 KB) (PDF/121.74 KB) (PDF/598.97 KB) (PDF/23.84 KB) (PDF/117.44 KB) • co-administration with QT-prolonging drugs, at the exception of apomorphine (see sections 4.4 and 4.5)
(PDF/120.44 KB) (PDF/495.21 KB) (PDF/96.43 KB) diltiazem, verapamil and some macrolides.Caution with bradycardia and hypokalaemia-inducing drugs, as well as with the following macrolides involved in QT-interval prolongation: azithromycin and roxithromycin (clarithromycin is contra-indicated as it is a potent CYP3A4 inhibitor).The above list of substances is representative and not exhaustive.With the combination of oral domperidone 10mg four times daily and ketoconazole 200mg twice daily, a mean QTc prolongation of 9.8 msec was seen over the observation period, with changes at individual time points ranging from 1.2 to 17.5 msec. • In patients who have known existing prolongation of cardiac conduction intervals, particularly QTc, patients with significant electrolyte disturbances or underlying cardiac diseases such as congestive heart failure (see section 4.4) (PDF/118.3 KB) (PDF/132.28 KB) (PDF/583.14 KB) Motilium Oral Suspension should be taken before meals/feeding. The Cmax and AUC values of domperidone increased proportionally with dose in the 10 mg to 20 mg dose range. (PDF/1.08 MB) (PDF/132.94 KB) (PDF/22.86 KB) There is no specific antidote to domperidone, but in the event of overdose, standard symptomatic treatment should be given immediately. (PDF/235.8 KB) (PDF/115.18 KB) (PDF/122.78 KB) (PDF/57.53 KB) (PDF/22.86 KB) (PDF/112.07 KB) Choice domperidone suppository 10mg negligently.Write something about yourself. (PDF/115.54 KB) (PDF/131.73 KB)
Domperidone motilium. (PDF/91.21 KB) (PDF/115.54 KB) (PDF/140.26 KB) (PDF/59.05 KB) (PDF/561.58 KB) (PDF/118.3 KB) (PDF/710.38 KB) (PDF/21.07 KB) (PDF/121.74 KB)
(PDF/114.21 KB) It must not be given to patients with moderate or severe impairment of liver function, or in those who have existing abnormalities of electrical activity in the heart or heart rhythm, or who are at increased risk of such effects. (PDF/585.02 KB) This study included a placebo, an active comparator and a positive control and was conducted in healthy subjects with up to 80 mg per day 10 or 20 mg administered 4 times a day of domperidone. What Motilium 10mg Film-Coated Tablets look like and contents of the pack The active substance is domperidone.
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