[1]Another woman taking a doses of 10, 20 and 30 mg every 8 hours on different days shortly after delivering a premature infant had peak milk levels 1 hour after each dose. Procardia XL [package insert]. Philadelphia (PA): Lippincott Williams & Wilkins;2005.National Library of Medicine (US). Eur J Clin Pharmacol. However, the difference was not statistically significant (p =0.0793). Nifedipine is used to treat painful nipple vasospasm (e.g., Raynaud phenomenon) in nursing mothers. Pediatrics. Trough milk samples were obtained between 15 and 30 days postpartum.
No adverse effects have been reported among infants exposed to nifedipine in breastmilk. In documented cases of women using the drug during breastfeeding, no harmful effects were seen in the infants. However, nifedipine has been used to decrease the pain of nipple vasospasm (or Raynaud phenomenon of the nipple), allowing mothers to continue nursing who might otherwise discontinue breastfeeding. Nifedipine transfer into human milk. [PubMedWu M, Chason R, Wong M. Raynaud's phenomenon of the nipple.
Another woman taking a doses of 10, 20 and 30 mg every 8 hours on different days shortly after delivering a premature infant had peak milk levels 1 hour after each dose. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Letter. [PubMedAnderson JE, Held N, Wright K. Raynaud's phenomenon of the nipple: A treatable cause of painful breastfeeding. 2013;149:300-6. Corona, CA: Watson Laboratories, Inc.;2005 July.Nifediac [package insert]. Lower dosages can be tried if these doses are not tolerated. 1989;114(3):478-80. One hour after this dose, peak milk levels of the drug and its pyridine metabolite were 43 and 15 mcg/L, respectively. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. [3]Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Gavreto (pralsetinib) is an oral selective RET kinase inhibitor for the...Detectnet (copper Cu 64 dotatate) is a radioactive diagnostic agent indicated...Onureg (azacitidine) is a nucleoside metabolic inhibitor indicated for the...Qdolo (tramadol hydrochloride) is an opioid agonist indicated in adults for ...The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
[1][7][8][9][10][13][14]Nifedipine had no effect on milk composition (sodium, potassium, calcium, chloride, nitrogen, phosphorus and total lipids) in one woman. 1991;11:231-6. [5]Nineteen hypertensive nursing mothers taking 20 mg of slow-release nifedipine daily for at least 15 days postpartum were genotyped for breast cancer resistance protein. Available for Android and iOS devices.Berens P, Eglash A, Malloy M et al. 2011;17:371-2. The highest milk level found was 53 mcg/L at 30 minutes after the 30 mg dose. It is used to treat high blood pressure (hypertension) and chest pain (angina).
Raynaud's phenomenon of the nipple: A preventable cause of breastfeeding failure? The average milk half-life of all doses was 3.3 hours. 7th ed. This site does not dispense medical advice or advice of any kind. 1996;166:448. New York, NY: Pfizer, Inc.;2003 August.Briggs GG, Freeman RK, Yaffe SJ. 2004;113(4):e360-4.
[6]No adverse reactions have been reported among infants exposed to nifedipine in breastmilk mostly at maternal dosages of 30 mg daily beginning shortly postpartum and continuing for up to 6 months in some. Site users seeking medical advice about their specific situation should consult with their own physician. [PubMedO'Sullivan S, Keith MP. New York, NY: Pfizer, Inc.;2006 May.
Some brand names for nifedipine are Procardia®, Adalat CC®, and Afeditab CR®.
Many sources report that nifedipine is probably compatible with breastfeeding, although the full risks are unknown.
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